SCHEMBL11684143

SCHEMBL11684143

CCCCCCCCN=C(NCCCCCCCC)c1ccc(CC(=O)O)cc1

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.50
HPGD P15428 3/20 0.48
HSD17B10 Q99714 1/20 0.48
NAAA Q02083 1/20 0.47
PLA2G4B P0C869 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TRPV1 Q8NER1 1/20 0.44
HDAC3 O15379 3/20 0.43
MLYCD O95822 1/20 0.42
EPHX1 P07099 1/20 0.42
HTT P42858 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11680051 0.85 ALDH1A1 (0.44) ALDH1A1HPGDHSD17B10HDAC3HTT
SCHEMBL9645773 0.82 NAAA (0.55) ALDH1A1HPGDNAAAHDAC3EPHX1
SCHEMBL9645767 0.82 NAAA (0.55) ALDH1A1HPGDNAAAHDAC3EPHX1
SCHEMBL3068162 0.74 NAAA (0.49) ALDH1A1HPGDNAAAHDAC3EPHX1
SCHEMBL3068165 0.74 NAAA (0.49) ALDH1A1HPGDNAAAHDAC3EPHX1
SCHEMBL7092632 0.74 EPHX1 (0.71) ALDH1A1EPHX1HTT
SCHEMBL11227278 0.73 ALDH1A1 (0.60) ALDH1A1HPGDHSD17B10PLA2G4BEPHX1
SCHEMBL11240393 0.73 ALDH1A1 (0.60) ALDH1A1HPGDHSD17B10PLA2G4BEPHX1
SCHEMBL11235403 0.73 ALDH1A1 (0.60) ALDH1A1HPGDHSD17B10PLA2G4BEPHX1
SCHEMBL11234116 0.73 ALDH1A1 (0.60) ALDH1A1HPGDHSD17B10PLA2G4BEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4016159-A BACTERICIDES HOECHST AKTIENGESELLSCHAFT (DT) 1977-04-05 US disclosed