Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 4/20 | 0.55 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645767 | 1.00 | NAAA (0.55) | NAAAEPHX1HTTALDH1A1HPGD | |
| SCHEMBL3068165 | 0.92 | NAAA (0.49) | NAAAEPHX1HTTALDH1A1HPGD | |
| SCHEMBL3068162 | 0.92 | NAAA (0.49) | NAAAEPHX1HTTALDH1A1HPGD | |
| SCHEMBL975934 | 0.83 | NAAA (0.42) | NAAAHDAC1 | |
| SCHEMBL11684143 | 0.82 | ALDH1A1 (0.50) | NAAAEPHX1HTTALDH1A1HPGD | |
| SCHEMBL3074605 | 0.77 | SCN5A (0.51) | HTTALDH1A1HPGDSMN1; SMN2HDAC3 | |
| SCHEMBL11781851 | 0.74 | CES2 (0.47) | NAAA | |
| SCHEMBL30762090 | 0.74 | CES2 (0.47) | NAAA | |
| SCHEMBL1003680 | 0.73 | NAAA (0.96) | NAAAHTTSMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL4838301 | 0.73 | CES2 (0.43) | NAAAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0346713-B1 | BENZAMIDINES USEFUL AS ULTRAVIOLET LIGHT ABSORBERS | L. GIVAUDAN & CIE Société Anonyme (CH) | 1992-09-16 | — | — | EP | disclosed |
| US-5011628-A | N,N'-diarylbenzamidines useful as ultraviolet light absorbers | GIVAUDAN CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| US-5011628-A | N,N'-diarylbenzamidines useful as ultraviolet light absorbers | GIVAUDAN CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0346713-A1 | Benzamidines useful as ultraviolet light absorbers | L. GIVAUDAN & CIE Société Anonyme (CH) | 1989-12-20 | — | — | EP | disclosed |