Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.57 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.56 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11685384 | 0.97 | DNMT3A (0.64) | DNMT3AHDAC1HDAC6NLRP3ABCB11 | |
| SCHEMBL11711852 | 0.93 | DNMT3A (0.66) | DNMT3AHDAC1HDAC6NLRP3KDM4E | |
| SCHEMBL11683540 | 0.91 | PPARA (0.54) | DNMT3AABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL10305346 | 0.89 | PPARA (0.54) | DNMT3ANLRP3ABCB11CYP1A2CYP3A4 | |
| SCHEMBL1154123 | 0.89 | DNMT3A (0.66) | DNMT3AHDAC1HDAC6NLRP3PPARA | |
| SCHEMBL11686019 | 0.87 | MAPT (0.50) | ABCB11CYP1A2CYP3A4TSHRHTR2A | |
| SCHEMBL10305304 | 0.87 | DNMT3A (0.47) | DNMT3AHDAC1HDAC6NLRP3ABCB11 | |
| SCHEMBL3687774 | 0.86 | DNMT3A (0.69) | DNMT3AHDAC1HDAC6NLRP3PPARA | |
| SCHEMBL10305274 | 0.85 | DNMT3A (0.66) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL11709070 | 0.85 | DNMT3A (0.55) | DNMT3AHDAC1HDAC6NLRP3ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010279-A | BIPHENYLOXY DERIVATIVES AND ANTIHYPERLIPIDEMIC USE | BOEHRINGER INGELHEIM GMBH (DT) | 1977-03-01 | — | — | US | claimed |
| US-4042711-A | Derivatives of biphenyloxy-lower alkanoic acids, salts thereof and their use as antihyperlipidemics | BOEHRINGER INGELHEIM GMBH (DT) | 1977-08-16 | — | — | US | disclosed |
| US-4010279-A | BIPHENYLOXY DERIVATIVES AND ANTIHYPERLIPIDEMIC USE | BOEHRINGER INGELHEIM GMBH (DT) | 1977-03-01 | — | — | US | disclosed |