Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11708524 | 0.92 | ALDH1A1 (0.48) | MAPTKDM4EKMT2AALDH1A1GAA | |
| SCHEMBL11708512 | 0.89 | TAAR1 (0.57) | MAPTKDM4EKMT2AALDH1A1GAA | |
| SCHEMBL11711918 | 0.89 | KDM4E (0.50) | MAPTKDM4EKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11682489 | 0.88 | KDM4E (0.64) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL11684158 | 0.87 | DNMT3A (0.61) | KDM4EALDH1A1PKMPPARAABCB11 | |
| SCHEMBL11708530 | 0.85 | PPARA (0.58) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL11707189 | 0.84 | PPARA (0.57) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL11685384 | 0.83 | DNMT3A (0.64) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL11709785 | 0.83 | USP2 (0.54) | MAPTKDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL11708965 | 0.83 | RAB9A (0.57) | MAPTKMT2AMEN1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042711-A | Derivatives of biphenyloxy-lower alkanoic acids, salts thereof and their use as antihyperlipidemics | BOEHRINGER INGELHEIM GMBH (DT) | 1977-08-16 | — | — | US | disclosed |
| US-4010279-A | BIPHENYLOXY DERIVATIVES AND ANTIHYPERLIPIDEMIC USE | BOEHRINGER INGELHEIM GMBH (DT) | 1977-03-01 | — | — | US | disclosed |