Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.66 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.61 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684158 | 0.93 | DNMT3A (0.61) | DNMT3AHDAC1HDAC6NLRP3KDM4E | |
| SCHEMBL1154123 | 0.92 | DNMT3A (0.66) | DNMT3AHDAC1HDAC6NLRP3KDM4E | |
| SCHEMBL11685384 | 0.89 | DNMT3A (0.64) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL3687774 | 0.89 | DNMT3A (0.69) | DNMT3AHDAC1HDAC6NLRP3KDM4E | |
| SCHEMBL10305274 | 0.88 | DNMT3A (0.66) | DNMT3AHDAC1HDAC6NLRP3 | |
| SCHEMBL11709070 | 0.88 | DNMT3A (0.55) | DNMT3AHDAC1HDAC6NLRP3ALDH1A1 | |
| SCHEMBL1153879 | 0.85 | ALDH1A1 (0.58) | DNMT3AHDAC1HDAC6NLRP3KDM4E | |
| SCHEMBL1154171 | 0.84 | DNMT3A (0.66) | DNMT3AHDAC1HDAC6NLRP3KDM4E | |
| SCHEMBL1153988 | 0.84 | DNMT3A (0.60) | DNMT3AHDAC1HDAC6NLRP3KDM4E | |
| SCHEMBL1154002 | 0.84 | DNMT3A (0.60) | DNMT3AHDAC1HDAC6NLRP3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4010279-A | BIPHENYLOXY DERIVATIVES AND ANTIHYPERLIPIDEMIC USE | BOEHRINGER INGELHEIM GMBH (DT) | 1977-03-01 | — | — | US | disclosed |