Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.40 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11687234 | 0.89 | RXRA (0.45) | RXRARXRBTSHRAKR1C3POLB | |
| SCHEMBL11598778 | 0.85 | TSHR (0.53) | TSHRAKR1C3HDAC1KDM4E | |
| SCHEMBL28422098 | 0.84 | KDM4E (0.52) | TSHRPOLBSRD5A2KDM4E | |
| SCHEMBL12062912 | 0.84 | NR4A2 (0.46) | TSHRKDM4C | |
| SCHEMBL8253839 | 0.83 | MRGPRX4 (0.48) | TSHRMRGPRX4MEN1KMT2AKDM4E | |
| SCHEMBL7918992 | 0.81 | AKR1C3 (0.54) | AKR1C3POLBMEN1KMT2AKDM4E | |
| SCHEMBL11687077 | 0.80 | CA1 (0.54) | AKR1C3POLBMRGPRX4MEN1KMT2A | |
| SCHEMBL9068428 | 0.80 | FOLH1 (0.56) | TSHRAKR1C3GPR52PDPK1KDM4E | |
| SCHEMBL18456911 | 0.79 | PTPRG (0.47) | KDM4CEGFRLCKMEN1KMT2A | |
| SCHEMBL28089634 | 0.78 | RXRA (0.49) | RXRARXRBPOLBCTDSP1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041173-A | ANTI-ASTHMATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1977-08-09 | — | — | US | disclosed |