Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29975597 | 0.87 | FOLH1 (0.66) | FOLH1TSHRALDH1A1ADRB2LMNA | |
| SCHEMBL166927 | 0.87 | FOLH1 (0.66) | FOLH1TSHRALDH1A1ADRB2LMNA | |
| Hydrochloric Acid SCHEMBL7699238 | 0.85 | FOLH1 (0.63) | FOLH1TSHRALDH1A1ADRB2LMNA | |
| SCHEMBL8702953 | 0.85 | FOLH1 (0.63) | FOLH1TSHRALDH1A1ADRB2LMNA | |
| SCHEMBL11782261 | 0.85 | SIRT2 (0.48) | TSHRALDH1A1ADRB2LMNAHTT | |
| SCHEMBL16950095 | 0.84 | TSHR (0.72) | FOLH1TSHRALDH1A1AKR1C3CA12 | |
| SCHEMBL7764255 | 0.84 | TSHR (0.72) | FOLH1TSHRALDH1A1ADRB2LMNA | |
| SCHEMBL70392 | 0.83 | FOLH1 (0.76) | FOLH1TSHRALDH1A1ADRB2AKR1C3 | |
| SCHEMBL30365583 | 0.83 | FOLH1 (0.76) | FOLH1TSHRALDH1A1ADRB2AKR1C3 | |
| SCHEMBL5515624 | 0.83 | FOLH1 (0.56) | FOLH1TSHRALDH1A1ADRB2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10476006-B2 | Compound and organic electronic device using the same | SHANGHAI NICHEM FINE CHEMICAL CO., LTD. (CN) | 2019-11-12 | — | — | US | disclosed |
| EP-3281936-B1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | SHANGHAI NICHEM FINE CHEMICAL CO LTD (CN) | 2019-10-09 | — | — | EP | disclosed |
| US-20180047908-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2018-02-15 | — | — | US | disclosed |
| US-20180047908-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | NICHEM FINE TECHNOLOGY CO., LTD. (TW) | 2018-02-15 | — | — | US | disclosed |
| EP-3281936-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | Nichem Fine Technology Co., Ltd. (TW) | 2018-02-14 | — | — | EP | disclosed |
| US-5492917-A | CARDIOVASCULAR DISORDERS; HYPOTENSIVE, ANTIISCHEMIC,ANTISHOCK, ANTIINFLAMMATORY, ANTIALLERGEN AGENTS | MERCK & CO., INC. (US) | 1996-02-20 | — | — | US | disclosed |
| WO-1995008989-A1 | ENDOTHELIN ANTAGONISTS INCORPORATING A CYCLOBUTANE | MERCK & CO., INC. (US) | 1995-04-06 | — | — | WO | disclosed |
| EP-0312051-B1 | Tricyclic compounds | KYOWA HAKKO KOGYO KK (JP) | 1994-08-17 | — | — | EP | disclosed |
| US-5010087-A | Cardiovascular disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-04-23 | — | — | US | disclosed |
| US-5010104-A | Antiischemic agent, cardiovascular disorders | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-04-23 | — | — | US | disclosed |
| US-4882351-A | CARDIOVASCULAR DISORDERS; | ROUSSEL UCLAF (FR) | 1989-11-21 | — | — | US | disclosed |
| EP-0312051-A2 | Tricyclic compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-04-19 | — | — | EP | disclosed |
| US-3988454-A | ANTIARRHYTHMICS | MERCK & CO., INC. (US) | 1976-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10476006-B2 | Compound and organic electronic device using the same | ESR1, AOC2, PIEZO1 | FOLH1 3893/4885TSHR 3504/4885ALDH1A1 71/4885 |
| US-20180047908-A1 | COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME | ESR1, AOC2, PIEZO1 | FOLH1 3893/4885TSHR 3504/4885ALDH1A1 71/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.