Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.50 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.50 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.50 |
| ▸ | TYMS | P04818 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11103185 | 0.73 | TDP1 (0.50) | TXNRD1TXNRD3TXNRD2POLBTDP1 | |
| SCHEMBL30999970 | 0.73 | TXNRD1 (0.42) | TXNRD1TXNRD3TXNRD2TYMSTDP1 | |
| SCHEMBL6972440 | 0.70 | DHFR (0.57) | TXNRD1TXNRD3TXNRD2TYMSALDH1A1 | |
| SCHEMBL21596907 | 0.70 | TYMS (0.43) | TXNRD1TXNRD3TXNRD2TYMSPOLB | |
| SCHEMBL27789837 | 0.70 | POLB (0.54) | TXNRD1TXNRD3TXNRD2TYMSPOLB | |
| SCHEMBL22978840 | 0.70 | CCNT1 (0.47) | TXNRD1TXNRD3TXNRD2TYMSPOLB | |
| SCHEMBL9722771 | 0.69 | BACE1 (0.40) | TYMSPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL2918933 | 0.68 | KMT2A (0.52) | TYMSPOLBTDP1ALDH1A1EGFR | |
| SCHEMBL65199 | 0.67 | TDP1 (0.61) | POLBTDP1ALDH1A1GPR35MEN1 | |
| SCHEMBL2213406 | 0.67 | TXNRD1 (1.00) | TXNRD1TXNRD3TXNRD2POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4028323-A | WITH A SUBSTITUTED AMINOBENZENE | CIBA-GEIGY AG (CH) | 1977-06-07 | — | — | US | disclosed |