Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8378461 | 0.73 | KDR (0.47) | TYMSTDP1MEN1KMT2AGAA | |
| SCHEMBL29652402 | 0.73 | KDR (0.47) | TYMSTDP1MEN1KMT2AGAA | |
| SCHEMBL93759 | 0.70 | TXNRD1 (0.54) | TXNRD1TXNRD3TXNRD2POLBTDP1 | |
| SCHEMBL11684263 | 0.70 | TXNRD1 (0.50) | TYMSTXNRD1TXNRD3TXNRD2POLB | |
| SCHEMBL21712254 | 0.70 | TXNRD1 (0.46) | TXNRD1TXNRD3TXNRD2POLBTDP1 | |
| SCHEMBL22978840 | 0.70 | CCNT1 (0.47) | TYMSTXNRD1TXNRD3TXNRD2POLB | |
| SCHEMBL27789837 | 0.70 | POLB (0.54) | TYMSTXNRD1TXNRD3TXNRD2POLB | |
| SCHEMBL6972440 | 0.70 | DHFR (0.57) | TYMSTXNRD1TXNRD3TXNRD2ALDH1A1 | |
| SCHEMBL21596942 | 0.69 | BACE1 (0.40) | TYMSSMN1; SMN2CA1CA2CA4 | |
| SCHEMBL21596915 | 0.69 | PARP1 (0.41) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3810602-A1 | COMPOUNDS | CTXT Pty Limited (AU) | 2021-04-28 | — | — | EP | disclosed |
| WO-2019243491-A1 | COMPOUNDS | CTXT PTY LIMITED (AU) | 2019-12-26 | — | — | WO | disclosed |