Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8934296 | 0.84 | LMNA (0.50) | LMNACYP1A2HIF1AL3MBTL1TSHR | |
| SCHEMBL8901516 | 0.84 | TP53 (0.57) | RAB9AMAOBMAPTMAOASMN1; SMN2 | |
| SCHEMBL8645545 | 0.82 | CA1 (0.49) | TSHRKMT2A | |
| SCHEMBL29090089 | 0.82 | CA1 (0.49) | TSHRKMT2A | |
| SCHEMBL11784051 | 0.82 | LMNA (0.47) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| Demannose SCHEMBL3007006 | 0.75 | TSHR (0.46) | CYP1A2CYP2C19MAPTTSHRKMT2A | |
| SCHEMBL10492673 | 0.75 | RAB9A (0.66) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL28234854 | 0.75 | CYP2C9 (0.46) | LMNAMAOBGAAMAPTSMN1; SMN2 | |
| SCHEMBL7688711 | 0.72 | LMNA (0.72) | LMNACYP1A2PTGS1SLC6A2CYP2C19 | |
| SCHEMBL8646883 | 0.72 | EPHX1 (0.42) | CYP1A2PTGS1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4049797-A | 1-PHENOXY-2-HYDROXY-3-AMINO-PROPANE-SUGAR COMPOUND | CIBA-GEIGY CORPORATION (US) | 1977-09-20 | — | — | US | disclosed |
| US-3978041-A | CARDIAC INSUFFICIENCY | CIBA-GEIGY CORPORATION (US) | 1976-08-31 | — | — | US | disclosed |