Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684378 | 0.84 | LMNA (0.49) | LMNAL3MBTL1KMT2ACYP1A2TSHR | |
| SCHEMBL28234854 | 0.83 | CYP2C9 (0.46) | LMNAADRB2ADRB1ADRB3MEN1 | |
| SCHEMBL9564637 | 0.79 | LMNA (0.68) | LMNAMTNR1AMTNR1BCYP2D6ADRB2 | |
| SCHEMBL4212363 | 0.78 | LMNA (0.57) | LMNAMTNR1AMTNR1BCYP2D6ADRB2 | |
| SCHEMBL8651047 | 0.77 | LMNA (0.52) | LMNAMTNR1AMTNR1BCYP2D6ADRB2 | |
| SCHEMBL978754 | 0.77 | LMNA (0.55) | LMNAMTNR1AMTNR1BCYP2D6ADRB2 | |
| SCHEMBL8588054 | 0.76 | TK1 (0.44) | LMNAALOX15CYP1A2TSHR | |
| SCHEMBL11800596 | 0.76 | TK1 (0.44) | LMNAALOX15CYP1A2TSHR | |
| SCHEMBL14917012 | 0.76 | ALDH1A1 (0.70) | LMNAADRB2ADRB1ADRB3L3MBTL1 | |
| SCHEMBL9294939 | 0.76 | ALDH1A1 (0.33) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031615-A1 | USE OF 2-DEOXYRIBOSE-5-PHOSPHATE ALDOLASE TO PREPARE 2-DEOXYFUCOSE, ANALOGUES AND DERIVATIVES | THE SCRIPPS RESEARCH INSTITUTE (US) | 1996-10-10 | — | — | WO | disclosed |