SCHEMBL11684388

SCHEMBL11684388

CCN(CCCS(=O)(=O)O)S(=O)(=O)c1ccc(N)c(Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SERPINE1 P05121 1/20 0.48
ALDH1A1 P00352 6/20 0.46
MAPT P10636 1/20 0.46
TSHR P16473 2/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
VCAM1 P19320 3/20 0.44
KDM4E B2RXH2 2/20 0.43
POLB P06746 1/20 0.42
ATM Q13315 1/20 0.42
CYP3A4 P08684 1/20 0.41
THRB P10828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11520364 0.94 SERPINE1 (0.49) SERPINE1ALDH1A1MAPTTSHRCA12
SCHEMBL10693591 0.85 ALDH1A1 (0.60) ALDH1A1MAPTTSHRCA12CA1
SCHEMBL11517824 0.80 CA12 (0.47) ALDH1A1TSHRCA12CA1CA2
SCHEMBL11685605 0.76 VCAM1 (0.59) ALDH1A1MAPTTSHRCA12CA1
SCHEMBL11517613 0.76 ALDH1A1 (0.50) ALDH1A1CA12CA1CA2CA9
SCHEMBL11518719 0.74 ALDH1A1 (0.43) SERPINE1ALDH1A1TSHRCA12CA1
SCHEMBL5461567 0.73 ALDH1A1 (0.65) ALDH1A1MAPTTSHRVCAM1KDM4E
SCHEMBL11682894 0.72 CYP2D6 (0.52) ALDH1A1TSHRCA12CA1CA2
SCHEMBL10694078 0.71 VCAM1 (0.65) ALDH1A1MAPTTSHRVCAM1KDM4E
SCHEMBL11685492 0.71 GAA (0.43) ALDH1A1MAPTTSHRVCAM1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4055557-A MONOAZO DYES BAYER AKTIENGESELLSCHAFT (DT) 1977-10-25 US disclosed