Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 3/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.35 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.35 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.35 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 2/20 | 0.34 |
| ▸ | FLT4 | P35916 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11683198 | 0.91 | TP53 (0.41) | TP53TSHRCCR2PTPN11CYP3A4 | |
| SCHEMBL11682328 | 0.89 | TP53 (0.44) | TP53TSHRCCR2PTPN11ALDH1A1 | |
| SCHEMBL11685849 | 0.88 | TSHR (0.45) | TP53TSHRCCR2PTPN11ALDH1A1 | |
| SCHEMBL11681974 | 0.83 | CYP2C9 (0.41) | TP53TSHRALDH1A1HSD17B10FLT1 | |
| SCHEMBL11682158 | 0.81 | TSHR (0.46) | TP53TSHRCCR2PTPN11CYP3A4 | |
| Aniline SCHEMBL11683885 | 0.79 | ALDH1A1 (0.44) | TSHRALDH1A1HSD17B10SUMO2SUMO1 | |
| SCHEMBL11684625 | 0.78 | SENP3 (0.43) | TP53TSHRPTPN11ALDH1A1HSD17B10 | |
| SCHEMBL11679955 | 0.77 | TSHR (0.37) | TSHRPTPN11CYP3A4ALDH1A1HSD17B10 | |
| SCHEMBL9636252 | 0.75 | ALDH1A1 (0.50) | TP53TSHRCYP3A4ALDH1A1HSD17B10 | |
| 3-Chloroaniline SCHEMBL11687359 | 0.75 | ALDH1A1 (0.47) | TSHRCCR2CYP3A4ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055557-A | MONOAZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-25 | — | — | US | disclosed |