Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.38 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.36 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684625 | 0.86 | SENP3 (0.43) | TSHRTP53SUMO2SUMO1SENP7 | |
| SCHEMBL11685849 | 0.85 | TSHR (0.45) | TSHRTP53ALDH1A1NT5EFLT1 | |
| SCHEMBL11682328 | 0.84 | TP53 (0.44) | TSHRTP53SUMO2SUMO1SENP7 | |
| SCHEMBL11684152 | 0.83 | TSHR (0.42) | TSHRTP53ALDH1A1FLT1FLT4 | |
| 3-Chloroaniline SCHEMBL11685285 | 0.82 | ALDH1A1 (0.49) | TSHRTP53SUMO2SUMO1SENP7 | |
| SCHEMBL11684850 | 0.81 | TP53 (0.41) | TSHRTP53SUMO2SUMO1SENP7 | |
| SCHEMBL11683198 | 0.81 | TP53 (0.41) | TSHRTP53ALDH1A1FLT1FLT4 | |
| SCHEMBL11681974 | 0.78 | CYP2C9 (0.41) | TSHRTP53ALDH1A1FLT1FLT4 | |
| SCHEMBL11684034 | 0.78 | ALDH1A1 (0.39) | TSHRTP53ALDH1A1CYP2C9POLB | |
| SCHEMBL11683452 | 0.76 | TP53 (0.41) | TSHRTP53CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055557-A | MONOAZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-25 | — | — | US | disclosed |