Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | F2 | P00734 | 3/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.55 |
| ▸ | HTR6 | P50406 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31134724 | 1.00 | CA1 (0.61) | CA1CA2CA9F2PRSS1 | |
| Formaldehyde SCHEMBL29980301 | 0.96 | CA1 (0.57) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL5684924 | 0.96 | CA1 (0.61) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL4888590 | 0.96 | CA1 (0.61) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL4886341 | 0.96 | CA1 (0.61) | CA1CA2CA9F2PRSS1 | |
| Potassium Ion SCHEMBL10962719 | 0.96 | CA1 (0.61) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL1948673 | 0.96 | CA1 (0.61) | CA1CA2CA9F2PRSS1 | |
| SCHEMBL295200 | 0.96 | CA1 (0.61) | CA1CA2CA9F2PRSS1 | |
| Zinc Ion SCHEMBL1683962 | 0.96 | CA1 (0.61) | CA1CA2CA9F2PRSS1 | |
| Potassium Ion SCHEMBL1305040 | 0.96 | CA1 (0.61) | CA1CA2CA9F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 297 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116396055-A | Ecological artificial stone with silt as main material and preparation method thereof | 浙江星创环保有限公司 | 2023-07-07 | — | — | CN | claimed |
| CN-116282783-A | Sludge pretreatment method for building materials | 浙江星创环保有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-115433376-A | Preparation method of long-acting disinfection and sterilization fabric or fiber | 孙国明 | 2022-12-06 | — | — | CN | claimed |
| CN-113998928-A | Environment-friendly micro-expansion waterproof building glue and use method thereof | 鞍钢建设集团有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-108026468-B | Seal swell agents for lubricating compositions | 路博润公司 | 2021-06-18 | — | — | CN | claimed |
| EP-3328973-B1 | SEAL SWELL AGENTS FOR LUBRICATING COMPOSITIONS | LUBRIZOL CORP (US) | 2020-07-01 | — | — | EP | claimed |
| US-10669504-B2 | Seal swell agents for lubrication compositions | THE LUBRIZOL CORPORATION (US) | 2020-06-02 | — | — | US | claimed |
| US-10611981-B2 | Mixed phosphorus esters for lubricant applications | THE LUBRIZOL CORPORATION (US) | 2020-04-07 | — | — | US | claimed |
| US-20180282654-A1 | MIXED PHOSPHORUS ESTERS FOR LUBRICANT APPLICATIONS | THE LUBRIZOL CORPORATION | 2018-10-04 | — | — | US | claimed |
| US-20180223214-A1 | SEAL SWELL AGENTS FOR LUBRICATING COMPOSITIONS | THE LUBRIZOL CORPORATION | 2018-08-09 | — | — | US | claimed |
| EP-2098492-A2 | ADDITIVE FOR THE PRODUCTION OF PERVIOUS ECOLOGICAL CONCRETE HAVING A HIGH RESISTANCE TO COMPRESSION, BENDING AND ABRASION AND THE PRODUCTION METHOD THEREOF | de Buen Unna, Néstor (MX) | 2009-09-09 | — | — | EP | claimed |
| US-6824605-B2 | MIXTURE OF DISPERSING AGENTS; HUMECTANT; HYDROXYPROPYL ETHYL OR METHYL CELLULOSE; AND FROM ABOUT 55.8% TO 64.2% BY WEIGHT OF A HIGHLY REACTIVE NON CRYSTALLINE CALCINATED SILICA ALUMINATE. | DE BUEN-UNNA NESTOR (MX) | 2004-11-30 | — | — | US | claimed |
| US-6660077-B2 | Dispersant; humectant; hydroxypropyl methyl (or ethyl) cellulose; a highly reactive non-crystalline calcinated silicon aluminate; optionally a nonionic surfactant, bactericide and antifoam agent | DE BUEN-UNNA NESTOR (MX) | 2003-12-09 | — | — | US | claimed |
| US-20030150362-A1 | Additive for the preparation of ecological permeable concretes with high compression, bending and abrasion resistance, and production process | DE BUEN-UNNA NESTOR (MX) | 2003-08-14 | — | — | US | claimed |
| US-20030061970-A1 | Additive for the preparation of ecological permeable concretes with high compression, bending and abrasion resistance, and production process | DE BUEN-UNNA NESTOR (MX) | 2003-04-03 | — | — | US | claimed |
| US-5629368-A | WATER, SODIUM SILICATE, ACRYLIC POLYMER | NALCO CANADA, INC. (CA) | 1997-05-13 | — | — | US | claimed |
| US-5484834-A | Liquid slurry of bentonite | NALCO CANADA INC. (CA) | 1996-01-16 | — | — | US | claimed |
| EP-0184346-B1 | PROCESS FOR PRODUCING CEMENT SHAPINGS FROM HYDRAULIC CEMENT COMPOSITION | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1989-09-06 | — | — | EP | claimed |
| US-4684407-A | Hydraulic cement composition and process for producing cement shapings | MITSUBISHI YUKA FINE CHEMICALS CO., LTD. (JP) | 1987-08-04 | — | — | US | claimed |
| EP-0184346-A1 | Process for producing cement shapings from hydraulic cement composition | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1986-06-11 | — | — | EP | claimed |