Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11681541 | 0.83 | NR1H3 (0.47) | PIK3CDPRKDCMAPTNPSR1LMNA | |
| SCHEMBL11682571 | 0.81 | ESR1 (0.46) | MAPTNPSR1LMNAALDH1A1CYP1A2 | |
| SCHEMBL11685049 | 0.80 | PRKDC (0.43) | PIK3CDPRKDCMAPTNPSR1LMNA | |
| SCHEMBL11682150 | 0.75 | KHK (0.44) | MAPTNPSR1LMNAALDH1A1KMT2A | |
| SCHEMBL11683265 | 0.72 | KDM4E (0.46) | PIK3CDPRKDCMAPTNPSR1LMNA | |
| SCHEMBL11684444 | 0.68 | KDM4E (0.46) | MAPTNPSR1LMNAALDH1A1MEN1 | |
| SCHEMBL13019686 | 0.66 | PIK3CD (0.68) | PIK3CDPRKDCCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11685205 | 0.65 | MAP2K4 (0.50) | MAPTNPSR1LMNAALDH1A1CYP1A2 | |
| SCHEMBL11688645 | 0.62 | L3MBTL1 (0.55) | MAPTLMNAALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11683676 | 0.62 | DHODH (0.39) | MAPTNPSR1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042704-A | FERTILITY CONTROL AGENTS | SANDOZ, INC. (US) | 1977-08-16 | — | — | US | claimed |
| US-4042704-A | FERTILITY CONTROL AGENTS | SANDOZ, INC. (US) | 1977-08-16 | — | — | US | disclosed |