Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | PAM | P19021 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30678931 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAPK1L3MBTL1PAMTSHR | |
| SCHEMBL8335056 | 0.82 | L3MBTL1 (0.41) | ALDH1A1MAPK1L3MBTL1PAMTSHR | |
| SCHEMBL24250955 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1PAMTSHR | |
| SCHEMBL4912321 | 0.81 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1PAMTSHR | |
| SCHEMBL9655848 | 0.80 | TDP1 (0.55) | ALDH1A1MAPK1L3MBTL1KMT2ASMN1; SMN2 | |
| SCHEMBL28521792 | 0.80 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1PAMTSHR | |
| Phenylacetic Acid SCHEMBL11794768 | 0.80 | AKR1B1 (0.55) | ALDH1A1MAPK1L3MBTL1PAMTSHR | |
| SCHEMBL2690493 | 0.79 | ALDH1A1 (0.68) | ALDH1A1MAPK1L3MBTL1PAMTSHR | |
| SCHEMBL8340762 | 0.78 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1PAMKMT2A | |
| SCHEMBL1434644 | 0.78 | ALDH1A1 (0.73) | ALDH1A1MAPK1L3MBTL1PAMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4031082-A | Process for preparing 3-acycloxymethyl-2-cephem compounds | ELI LILLY AND COMPANY (US) | 1977-06-21 | — | — | US | disclosed |
| US-4029651-A | ESTERIFICATION | ELI LILLY AND COMPANY (US) | 1977-06-14 | — | — | US | disclosed |