SCHEMBL8340762

SCHEMBL8340762

O=C(Cc1ccc(CO)cc1)OCc1ccc(CC(=O)OCC(Cl)(Cl)Cl)cc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
MAPK1 P28482 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
ENPP2 Q13822 1/20 0.38
MAPT P10636 2/20 0.38
POLB P06746 2/20 0.37
PAM P19021 1/20 0.37
PPARG P37231 3/20 0.36
PPARA Q07869 3/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CYP4F2 P78329 1/20 0.36
CYP4A11 Q02928 1/20 0.36
LIPE Q05469 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8117331 0.80 ALDH1A1 (0.82) ALDH1A1MAPK1L3MBTL1ENPP2PAM
SCHEMBL8335056 0.79 L3MBTL1 (0.41) ALDH1A1MAPK1L3MBTL1MAPTPOLB
SCHEMBL8340767 0.78 CRHBP (0.35) L3MBTL1MAPTPOLBKMT2ACYP4F2
SCHEMBL11686013 0.78 ALDH1A1 (0.61) ALDH1A1MAPK1L3MBTL1PAMKMT2A
SCHEMBL30679011 0.78 CYP4F2 (0.36) ALDH1A1MAPK1L3MBTL1MAPTPOLB
SCHEMBL10226654 0.74 ALDH1A1 (0.48) ALDH1A1MAPK1L3MBTL1MAPTPOLB
SCHEMBL6784181 0.72 ALDH1A1 (0.96) ALDH1A1MAPK1L3MBTL1ENPP2PAM
SCHEMBL28250075 0.72 ALDH1A1 (0.66) ALDH1A1MAPK1L3MBTL1MAPTPPARG
SCHEMBL9655848 0.71 TDP1 (0.55) ALDH1A1MAPK1L3MBTL1MAPTKMT2A
SCHEMBL13932524 0.71 ALDH1A1 (0.66) ALDH1A1MAPK1L3MBTL1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5998595-A Azidohalogenobenzyl derivatives, sugar compounds and protection of hydroxy groups WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1999-12-07 US disclosed