Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11686667 | 0.91 | LMNA (0.59) | LMNAPOLBTP53EPHX2 | |
| SCHEMBL135086 | 0.91 | LMNA (0.58) | LMNAPOLBTP53EPHX2 | |
| SCHEMBL11685301 | 0.89 | LMNA (0.67) | LMNAPOLBTP53EPHX2 | |
| SCHEMBL11686660 | 0.88 | LMNA (0.55) | LMNAPOLBTP53EPHX2 | |
| SCHEMBL11683384 | 0.88 | LMNA (0.55) | LMNAPOLBTP53EPHX2 | |
| SCHEMBL11686263 | 0.85 | TSHR (0.51) | LMNAPOLBTP53EPHX2 | |
| SCHEMBL11651942 | 0.81 | TP53 (0.58) | LMNAPOLBTP53 | |
| SCHEMBL11686317 | 0.81 | LMNA (0.56) | LMNAPOLBTP53EPHX2 | |
| SCHEMBL11683976 | 0.80 | LMNA (0.55) | LMNAPOLBTP53EPHX2 | |
| SCHEMBL11683088 | 0.80 | TP53 (0.57) | LMNAPOLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4013452-A | Urea derivatives and their use as herbicides | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-03-22 | — | — | US | disclosed |
| US-3937726-A | UREA DERIVATIVES AND THEIR USE AS HERBICIDES | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-02-10 | — | — | US | disclosed |