Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 10/20 | 0.64 |
| ▸ | HTR1A | P08908 | 5/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.56 |
| ▸ | DRD3 | P35462 | 5/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | USP2 | O75604 | 4/20 | 0.56 |
| ▸ | DRD2 | P14416 | 4/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.56 |
| ▸ | HTR2A | P28223 | 4/20 | 0.56 |
| ▸ | HRH1 | P35367 | 4/20 | 0.56 |
| ▸ | HTR2B | P41595 | 4/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11688573 | 0.99 | KDM1A (0.62) | KDM1AHTR1ASLC6A2SLC6A4ADRA1A | |
| Hydrochloric Acid SCHEMBL11688023 | 0.92 | KDM1A (0.56) | KDM1AFPR2 | |
| SCHEMBL11686342 | 0.91 | CYP2D6 (0.72) | KDM1AHTR1ASLC6A2SLC6A4ADRA1A | |
| Hydrochloric Acid SCHEMBL11690756 | 0.90 | LMNA (0.71) | KDM1AHTR1ASLC6A2SLC6A4ADRA1A | |
| SCHEMBL11688791 | 0.89 | KDM1A (0.58) | KDM1AHTR1ASLC6A2SLC6A4ADRA1A | |
| SCHEMBL11684759 | 0.88 | KDM1A (0.57) | KDM1AHTR1ASLC6A2SLC6A4ADRA1A | |
| Flupimazine SCHEMBL2109271 | 0.88 | FPR2 (0.75) | HTR1ASLC6A2SLC6A4ADRA1ADRD3 | |
| Hydrochloric Acid SCHEMBL11690805 | 0.87 | KDM1A (0.56) | KDM1AHTR1ASLC6A2SLC6A4ADRA1A | |
| Flupimazine SCHEMBL11684459 | 0.87 | LMNA (0.74) | HTR1ASLC6A2SLC6A4ADRA1ADRD3 | |
| SCHEMBL11686356 | 0.83 | FPR2 (0.73) | HTR1ASLC6A2SLC6A4ADRA1ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018922-A | NEUROLEPTICS, ANALGESICS, SPASMOLYTICS, AND ANTIHISTAMINES | ROUSSEL-UCLAF (FR) | 1977-04-19 | — | — | US | disclosed |