Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11634995 | 0.88 | POLB (0.51) | SMN1; SMN2MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL11626582 | 0.86 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1CYP1A2KMT2AALDH1A1 | |
| SCHEMBL11835158 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2MEN1CYP1A2KMT2AALDH1A1 | |
| SCHEMBL11836968 | 0.84 | SMN1; SMN2 (0.55) | SMN1; SMN2MEN1CYP1A2KMT2AALDH1A1 | |
| SCHEMBL11689676 | 0.82 | TP53 (0.49) | SMN1; SMN2MEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL11690673 | 0.79 | CA1 (0.43) | SMN1; SMN2MEN1KMT2APOLBCA1 | |
| SCHEMBL11489705 | 0.78 | SMN1; SMN2 (0.61) | SMN1; SMN2MEN1CYP1A2KMT2AALDH1A1 | |
| SCHEMBL11669564 | 0.77 | ALDH1A1 (0.51) | SMN1; SMN2MEN1CYP1A2KMT2AALDH1A1 | |
| SCHEMBL11703246 | 0.77 | ALDH1A1 (0.54) | SMN1; SMN2MEN1KMT2AALDH1A1CYP2C9 | |
| SCHEMBL11708080 | 0.77 | MEN1 (0.53) | SMN1; SMN2MEN1CYP1A2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4056383-A | Thiaoiazolyltetrahydropyrimidinone herbicides | VELSICOL CHEMICAL CORPORATION (US) | 1977-11-01 | — | — | US | disclosed |
| US-4053298-A | HERBICIDAL COMPOSITIONS CONTAINING 1-THIADIAZOLYL-6-CARBAMOYLOXYTETRAHYDROPYRIMIDINONES AND METHODS THEREFOR | VELSICOL CHEMICAL CORPORATION (US) | 1977-10-11 | — | — | US | disclosed |
| US-4040812-A | Herbicidal carbonates and thiocarbonates of thiadiazolyl-2(1H)-pyrimidinones | VELSICOL CHEMICAL CORPORATION (US) | 1977-08-09 | — | — | US | disclosed |
| US-4006009-A | 1-Thiadiazolyl-6-acyloxytetrahydropyrimidinone herbicides | VELSICOL CHEMICAL CORPORATION (US) | 1977-02-01 | — | — | US | disclosed |
| US-3988143-A | 1-Thiadiazolyl-6-alkoxytetrahydropyrimidinones | VELSICOL CHEMICAL CORPORATION (US) | 1976-10-26 | — | — | US | disclosed |
| US-3979388-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1976-09-07 | — | — | US | disclosed |
| US-3951976-A | 1-Thiadiazoly-6-carbamoyloxytetrahydropyrimidinones | VELSICOL CHEMICAL CORPORATION (US) | 1976-04-20 | — | — | US | disclosed |
| US-3932410-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |