Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA3 | P07451 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.37 |
| ▸ | CA6 | P23280 | 2/20 | 0.37 |
| ▸ | CA5A | P35218 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.37 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11203275 | 0.79 | EPAS1 (0.38) | IKBKBCHUKLRRK2LMNAALDH1A1 | |
| SCHEMBL2308454 | 0.75 | SMN1; SMN2 (0.36) | IKBKBCHUKSMN1; SMN2GAACA12 | |
| SCHEMBL11686066 | 0.75 | FEN1 (0.39) | TSHRCYP3A4 | |
| SCHEMBL11519787 | 0.75 | ALDH1A1 (0.40) | SMN1; SMN2GAALMNAL3MBTL1ALDH1A1 | |
| SCHEMBL10153815 | 0.74 | ACLY (0.53) | SMN1; SMN2GAACA12CA1CA2 | |
| SCHEMBL19771455 | 0.71 | LMNA (0.54) | IKBKBCHUKSMN1; SMN2GAACA12 | |
| SCHEMBL11594800 | 0.71 | SMN1; SMN2 (0.46) | SMN1; SMN2GAACA12CA1CA2 | |
| SCHEMBL11686141 | 0.71 | CA1 (0.57) | SMN1; SMN2GAACA12CA1CA2 | |
| SCHEMBL11682482 | 0.71 | CA1 (0.59) | SMN1; SMN2GAACA12CA1CA2 | |
| SCHEMBL20779880 | 0.68 | CA1 (0.48) | SMN1; SMN2CA1CA2CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4026931-A | AZO DYES, FIBER-REACTIVE; INDOLE OR 5-AMINO-PYRAZOLE COUPLING COMPONENT | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |