Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11645332 | 0.87 | MTNR1B (0.53) | MAPTNPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11644420 | 0.86 | ALDH1A1 (0.54) | MAPTNPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11644996 | 0.85 | XIAP (0.50) | MAPTNPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11689720 | 0.84 | ALDH1A1 (0.59) | MAPTNPC1LMNAMTNR1BALDH1A1 | |
| SCHEMBL11645520 | 0.84 | ALDH1A1 (0.56) | MAPTNPC1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11644068 | 0.78 | MTNR1B (0.47) | NPC1KMT2ASMN1; SMN2MTNR1BALDH1A1 | |
| SCHEMBL11643296 | 0.77 | XIAP (0.52) | MAPTNPC1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL11646067 | 0.77 | XIAP (0.54) | MAPTNPC1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11642716 | 0.77 | MTNR1B (0.64) | NPC1KMT2ASMN1; SMN2MTNR1BALDH1A1 | |
| SCHEMBL11645067 | 0.77 | XIAP (0.56) | MEN1KMT2ASMN1; SMN2LMNAMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4032655-A | PHENYLGUANIDINES USEFUL AS ANTHELMINTIC AGENTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-06-28 | — | — | US | disclosed |