Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | HSD11B1 | P28845 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6492730 | 0.87 | HSD11B1 (0.50) | KMT2AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL28259492 | 0.85 | KMT2A (0.65) | KMT2AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL11658428 | 0.78 | KMT2A (0.73) | KMT2AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL10103705 | 0.76 | KMT2A (0.76) | KMT2AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL29933328 | 0.75 | KMT2A (0.69) | KMT2AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL11663451 | 0.75 | KMT2A (0.69) | KMT2AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL1605984 | 0.74 | MAPT (0.51) | KMT2AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL2967926 | 0.73 | KMT2A (0.54) | KMT2AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL22004306 | 0.73 | ACLY (0.49) | KMT2AKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL2963932 | 0.73 | KDM4E (0.50) | KMT2AKDM4EALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4026931-A | AZO DYES, FIBER-REACTIVE; INDOLE OR 5-AMINO-PYRAZOLE COUPLING COMPONENT | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |