Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7113669 | 0.88 | MAPT (0.62) | MAPTTAAR1ALDH1A1CYP3A4HTR3E | |
| SCHEMBL11689257 | 0.87 | MAPT (0.58) | MAPTTAAR1ALDH1A1CYP3A4HTR3E | |
| SCHEMBL2468699 | 0.86 | MAPT (0.56) | MAPTTAAR1ALDH1A1CYP3A4HTR3E | |
| SCHEMBL11517338 | 0.82 | ALDH1A1 (0.55) | MAPTTAAR1ALDH1A1CYP3A4HTR3E | |
| SCHEMBL5551845 | 0.82 | MAPT (0.51) | MAPTTAAR1ALDH1A1CYP3A4AOC3 | |
| SCHEMBL11691833 | 0.82 | MAPT (0.51) | MAPTTAAR1ALDH1A1CYP3A4AOC3 | |
| SCHEMBL11133767 | 0.81 | MAPT (0.65) | MAPTTAAR1ALDH1A1CYP3A4HTR3E | |
| SCHEMBL10797168 | 0.80 | MAPT (0.50) | MAPTTAAR1ALDH1A1CYP3A4HTR3E | |
| SCHEMBL11793328 | 0.80 | MAPT (0.50) | MAPTTAAR1ALDH1A1CYP3A4HPGD | |
| SCHEMBL681549 | 0.79 | ALDH1A1 (0.48) | MAPTALDH1A1CYP3A4HPGDIGLV6-57 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4059402-A | SUBLIMATION, MONOAZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-22 | — | — | US | disclosed |