Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | THRA | P10827 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397442 | 0.83 | GFER (0.54) | MAPTKMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL11714694 | 0.83 | SMN1; SMN2 (0.48) | MAPTKMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL8018555 | 0.82 | KMT2A (0.54) | MAPTKMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL16617204 | 0.82 | ALDH1A1 (0.44) | MAPTKMT2AMEN1SMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL11594933 | 0.82 | GFER (0.53) | MAPTKMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL10794734 | 0.81 | MAPT (0.50) | MAPTKMT2AMEN1SMN1; SMN2HTT | |
| SCHEMBL11505543 | 0.81 | EPHX2 (0.45) | MAPTKMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL2468699 | 0.81 | MAPT (0.56) | MAPTKMT2AMEN1SMN1; SMN2GAA | |
| SCHEMBL11694232 | 0.80 | MAPT (0.59) | MAPTKMT2AMEN1SMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL8940098 | 0.80 | KMT2A (0.53) | MAPTKMT2AMEN1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3945991-A | Heterocyclic azo compounds containing a quaternated hydrazide group | CIBA-GEIGY AG (CH) | 1976-03-23 | — | — | US | disclosed |