Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | STK4 | Q13043 | 1/20 | 0.45 |
| ▸ | STK3 | Q13188 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 4/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2767092 | 0.89 | MAPT (0.69) | MAPTTAAR1ALDH1A1STK4STK3 | |
| SCHEMBL30197830 | 0.89 | MAPT (0.69) | MAPTTAAR1ALDH1A1STK4STK3 | |
| SCHEMBL11694232 | 0.86 | MAPT (0.59) | MAPTTAAR1ALDH1A1CYP3A4HTT | |
| SCHEMBL7113669 | 0.85 | MAPT (0.62) | MAPTTAAR1ALDH1A1CYP3A4HTR3E | |
| SCHEMBL11689257 | 0.84 | MAPT (0.58) | MAPTTAAR1ALDH1A1CYP3A4HTT | |
| SCHEMBL11067328 | 0.82 | ALDH1A1 (0.60) | MAPTALDH1A1CYP3A4HTTS1PR1 | |
| SCHEMBL11793328 | 0.81 | MAPT (0.50) | MAPTTAAR1ALDH1A1CYP3A4HTT | |
| SCHEMBL10797168 | 0.81 | MAPT (0.50) | MAPTTAAR1ALDH1A1CYP3A4HTT | |
| SCHEMBL29872680 | 0.81 | ALDH1A1 (0.50) | MAPTALDH1A1CYP3A4HTTKMT2A | |
| SCHEMBL61069 | 0.81 | ALDH1A1 (0.76) | MAPTALDH1A1CYP3A4S1PR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362082-B1 | COLOURED, WATER-DISSIPATABLE POLYURETHANES | FUJIFILM IMAGING COLORANTS LTD (GB) | 2011-10-05 | — | — | EP | disclosed |
| US-20040102542-A1 | Coloured, water-dissipatable polyurethanes | AVECIA LIMITED (GB) | 2004-05-27 | — | — | US | disclosed |
| EP-1362082-A1 | COLOURED, WATER-DISSIPATABLE POLYURETHANES | Avecia Limited (GB) | 2003-11-19 | — | — | EP | disclosed |
| WO-2002050197-A1 | COLOURED, WATER-DISSIPATABLE POLYURETHANES | AVECIA LIMITED (GB) | 2002-06-27 | — | — | WO | disclosed |
| US-4041025-A | FOR HYDROPHOBIC FIBERS SUCH AS POLYESTERS, YELLOW TO BLUE-GREEN SHADES | BASF AKTIENGESELLSCHAFT (DT) | 1977-08-09 | — | — | US | disclosed |