Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11692886 | 0.87 | NPC1 (0.52) | NPC1RAB9ARECQLALDH1A1GAA | |
| SCHEMBL11696525 | 0.84 | GAA (0.50) | NPC1RAB9ARECQLALDH1A1GAA | |
| SCHEMBL11693290 | 0.82 | NPC1 (0.71) | NPC1RAB9ARECQLALDH1A1GAA | |
| SCHEMBL31472623 | 0.73 | GAA (0.53) | NPC1RAB9AALDH1A1GAATDP1 | |
| SCHEMBL11698826 | 0.72 | EPHX2 (0.50) | NPC1RAB9AALDH1A1EPHX2HTT | |
| SCHEMBL173657 | 0.71 | ALDH1A1 (0.54) | NPC1RAB9AALDH1A1GAAHTT | |
| SCHEMBL11695743 | 0.70 | NPC1 (0.74) | NPC1RAB9ARECQLALDH1A1GAA | |
| SCHEMBL9901421 | 0.67 | EPHX2 (0.36) | NPC1RAB9ARECQLALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL11697560 | 0.66 | NPC1 (0.64) | NPC1RAB9ARECQLALDH1A1GAA | |
| SCHEMBL31472621 | 0.66 | EPHX2 (0.47) | NPC1RAB9ARECQLALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051256-A | ANTIRHINOVIRUS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (EN) | 1977-09-27 | — | — | US | claimed |
| US-4051256-A | ANTIRHINOVIRUS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (EN) | 1977-09-27 | — | — | US | disclosed |