Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.71 |
| ▸ | RAB9A | P51151 | 2/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11695743 | 0.87 | NPC1 (0.74) | NPC1RAB9ARECQLGAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL11697560 | 0.83 | NPC1 (0.64) | NPC1RAB9ARECQLGAAALDH1A1 | |
| SCHEMBL11695331 | 0.82 | NPC1 (0.50) | NPC1RAB9ARECQLGAAALDH1A1 | |
| SCHEMBL31472623 | 0.73 | GAA (0.53) | NPC1RAB9AGAAALDH1A1TDP1 | |
| SCHEMBL6843046 | 0.73 | ALDH1A1 (0.73) | NPC1RAB9ARECQLGAAALDH1A1 | |
| SCHEMBL10069054 | 0.72 | TASP1 (1.00) | NPC1RAB9ARECQLGAAALDH1A1 | |
| SCHEMBL10099725 | 0.71 | GAA (0.83) | GAAALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL11692886 | 0.70 | NPC1 (0.52) | NPC1RAB9ARECQLGAAALDH1A1 | |
| SCHEMBL2243666 | 0.69 | ALDH1A1 (0.67) | NPC1RAB9ARECQLGAAALDH1A1 | |
| SCHEMBL4257551 | 0.68 | GAA (0.58) | NPC1RAB9ARECQLGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4051256-A | ANTIRHINOVIRUS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (EN) | 1977-09-27 | — | — | US | disclosed |