SCHEMBL173657

SCHEMBL173657

N=C(Nc1ccc(F)cc1)Nc1ccc(F)cc1

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.54
GAA P10253 2/20 0.50
IDO1 P14902 1/20 0.50
MEN1 O00255 6/20 0.48
KMT2A Q03164 6/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
MAPK1 P28482 1/20 0.48
TGM2 P21980 1/20 0.48
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
POLB P06746 2/20 0.47
HTT P42858 1/20 0.47
TAAR1 Q96RJ0 1/20 0.47
PTPN1 P18031 1/20 0.47
NOX1 Q9Y5S8 1/20 0.47
MITF O75030 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27214949 0.91 NOX1 (0.60) ALDH1A1MEN1KMT2ASMN1; SMN2LMNA
SCHEMBL19382690 0.86 ALDH1A1 (0.47) ALDH1A1GAAIDO1MEN1KMT2A
SCHEMBL3674744 0.83 ALDH1A1 (0.53) ALDH1A1GAAIDO1MEN1KMT2A
Hydrochloric Acid SCHEMBL16702582 0.81 ALDH1A1 (0.52) ALDH1A1GAAIDO1MEN1KMT2A
SCHEMBL19373774 0.80 MEN1 (0.52) ALDH1A1GAAIDO1MEN1KMT2A
SCHEMBL3114418 0.80 ALDH1A1 (0.50) ALDH1A1GAAIDO1MEN1KMT2A
SCHEMBL4029597 0.80 ALDH1A1 (0.61) ALDH1A1GAAIDO1MEN1KMT2A
SCHEMBL12505836 0.80 MEN1 (0.56) ALDH1A1GAAIDO1MEN1KMT2A
SCHEMBL3973745 0.80 ALDH1A1 (0.55) ALDH1A1GAAMEN1KMT2ASMN1; SMN2
Hydrochloric Acid SCHEMBL4372005 0.80 ALDH1A1 (0.50) ALDH1A1GAAIDO1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11559763-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (US) 2023-01-24 US claimed
US-20260007998-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2026-01-08 US disclosed
US-12427471-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (NC) 2025-09-30 US disclosed
EP-4359111-A1 MBZA/PEG ETHYL ETHER BASED LIQUID SOLVENT CO2 CAPTURE IN ROTATING PACKED BED Research Triangle Institute (US) 2024-05-01 EP disclosed
CN-117597184-A MBZA/PEG diethyl ether based liquid solvent CO in a rotating packed bed 2 Capturing 研究三角协会 2024-02-23 CN disclosed
US-20230241547-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2023-08-03 US disclosed
US-11612854-B2 Non-aqueous solvent CO2 capture in rotating packed bed RESEARCH TRIANGLE INSTITUTE (US) 2023-03-28 US disclosed
US-11559763-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (US) 2023-01-24 US disclosed
WO-2022269546-A1 MBZA/PEG ETHYL ETHER BASED LIQUID SOLVENT CO2 CAPTURE IN ROTATING PACKED BED RESEARCH TRIANGLE INSTITUTE (US) 2022-12-29 WO disclosed
US-20220410063-A1 NON-AQUEOUS SOLVENT CO2 CAPTURE IN ROTATING PACKED BED RESEARCH TRIANGLE INSTITUTE 2022-12-29 US disclosed
US-20180345206-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2018-12-06 US disclosed
US-10065148-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (US) 2018-09-04 US disclosed
US-9839875-B2 Regenerable solvent mixtures for acid-gas separation RESEARCH TRIANGLE INSTITUTE (US) 2017-12-12 US disclosed
EP-2611518-B1 REGENERABLE IONIC LIQUID SOLVENTS FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2016-08-24 EP disclosed
US-20150328581-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RES TRIANGLE INST (US) 2015-11-19 US disclosed
EP-2611518-A1 REGENERABLE IONIC LIQUID SOLVENTS FOR ACID -GAS SEPARATION Research Triangle Institute (US) 2013-07-10 EP disclosed
US-20130164199-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION RESEARCH TRIANGLE INSTITUTE 2013-06-27 US disclosed
US-8147735-B2 Semipermeable polymers and method for producing same ELTRON RESEARCH & DEVELOPMENT, INC. (US) 2012-04-03 US disclosed
WO-2012031274-A1 REGENERABLE IONIC LIQUID SOLVENTS FOR ACID -GAS SEPARATION RESEARCH TRIANGLE INSTITUTE (US) 2012-03-08 WO disclosed
US-20100006495-A1 SEMIPERMEABLE POLYMERS AND METHOD FOR PRODUCING SAME ELTRON RESEARCH AND DEVELOPMENT, INC. (US) 2010-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260007998-A1 REGENERABLE SOLVENT MIXTURES FOR ACID-GAS SEPARATION NOS2, DUOX2, SMOX ALDH1A1 3356/4885GAA 4730/4885IDO1 1153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.