Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 6/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.44 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 4/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 4/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 4/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12200306 | 0.85 | CA2 (0.71) | CA2CA1CA9 | |
| SCHEMBL11716215 | 0.85 | CA2 (0.49) | CA2CA1CA9LRRK2ALDH1A1 | |
| SCHEMBL11699688 | 0.84 | ALDH1A1 (0.45) | CA2CA1CA9BCL2L1NPC1 | |
| SCHEMBL11696852 | 0.79 | CA2 (0.46) | CA2CA1CA9BCL2L1NPC1 | |
| SCHEMBL6534678 | 0.78 | KMT2A (0.56) | CA2CA1 | |
| SCHEMBL9484070 | 0.76 | NPC1 (0.57) | CA2CA1CA9NPC1ALDH1A1 | |
| SCHEMBL10206324 | 0.74 | CRHBP (0.49) | CA2CA1CA9ALDH1A1CYP3A4 | |
| SCHEMBL2679084 | 0.73 | MAPT (0.54) | CA2CA1CA9ALDH1A1CYP3A4 | |
| SCHEMBL30343460 | 0.73 | MAPT (0.54) | CA2CA1CA9ALDH1A1CYP3A4 | |
| Sulfuric Acid SCHEMBL11089366 | 0.73 | ALDH1A1 (0.61) | CA2CA1CA9ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041208-A | ENERGY ABSORBERS, LAMINATED GLASS SHEETS USEFUL AS AUTOMOBILE WINDSHIELDS | PPG INDUSTRIES, INC. (US) | 1977-08-09 | — | — | US | disclosed |