Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | CCKBR | P32239 | 2/20 | 0.50 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 11/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.40 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11698436 | 0.90 | CTSS (0.54) | CTSSCTSKCCKBRRENCA2 | |
| SCHEMBL11694126 | 0.88 | CTSK (0.50) | CTSSCTSKCCKBRRENCA2 | |
| SCHEMBL11697858 | 0.84 | CCKBR (0.76) | CTSSCTSKCCKBRMAPT | |
| SCHEMBL11696339 | 0.84 | CTSS (0.48) | CTSSCTSKCCKBRRENCA2 | |
| Hydrochloric Acid SCHEMBL11697602 | 0.83 | DPP4 (0.38) | — | |
| SCHEMBL11699180 | 0.82 | CTSS (0.55) | CTSSCTSKCCKBRRENCA2 | |
| SCHEMBL11696148 | 0.82 | CTSS (0.57) | CTSSCTSKCCKBRRENCA2 | |
| SCHEMBL6982979 | 0.81 | CTSS (0.64) | CTSSCTSKCCKBRRENCA2 | |
| SCHEMBL11698208 | 0.81 | CTSS (0.55) | CTSSCTSKCCKBRRENCA2 | |
| SCHEMBL11695783 | 0.79 | CTSS (0.56) | CTSSCTSKCCKBRRENCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4012367-A | Anti-ulcer polypeptides containing L-aspartic acid and intermediates thereto | G. D. SEARLE & CO. (US) | 1977-03-15 | — | — | US | disclosed |