Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11698499 | 0.78 | KDM4E (0.42) | ALDH1A1CYP3A4CA2LMNAEPHX1 | |
| SCHEMBL1170830 | 0.76 | ALDH1A1 (0.49) | ALDH1A1CYP3A4CA2LMNARAB9A | |
| SCHEMBL11697335 | 0.76 | PPARG (0.46) | ALDH1A1CYP3A4CA2LMNARAB9A | |
| SCHEMBL18837355 | 0.74 | CA2 (0.48) | ALDH1A1CYP3A4CA2LMNARAB9A | |
| SCHEMBL21035561 | 0.74 | SMN1; SMN2 (0.49) | ALDH1A1CYP3A4LMNARAB9ASMN1; SMN2 | |
| SCHEMBL11696233 | 0.71 | SMN1; SMN2 (0.40) | ALDH1A1CYP3A4LMNARAB9ASMN1; SMN2 | |
| SCHEMBL27768843 | 0.68 | ALOX5 (0.49) | RAB9ANPC1CYP1A2KDM4EMAPK1 | |
| SCHEMBL22499622 | 0.68 | TDP1 (0.46) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL11698426 | 0.68 | ALDH1A1 (0.41) | ALDH1A1CYP3A4CA2LMNAPRSS1 | |
| SCHEMBL11883192 | 0.67 | ALDH1A1 (0.49) | ALDH1A1CYP3A4CA2LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000985-A | DISAZO | MORTON-NORWICH PRODUCTS, INC. (US) | 1977-01-04 | — | — | US | disclosed |