Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1690453 | 0.90 | CYP19A1 (0.47) | ESR1MAPTMEN1KMT2ACYP19A1 | |
| SCHEMBL11546766 | 0.85 | ESR1 (0.40) | ESR1MEN1KMT2ACYP19A1CYP11B2 | |
| SCHEMBL11699124 | 0.76 | ESR1 (0.64) | ESR1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL11767544 | 0.76 | AKR1C1 (0.51) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL11403405 | 0.76 | NFE2L2 (0.34) | MEN1KMT2ANPSR1CA1CA2 | |
| SCHEMBL10790252 | 0.76 | KMT2A (0.46) | MAPTMEN1KMT2ANPSR1NPC1 | |
| SCHEMBL11087246 | 0.73 | MTNR1A (0.43) | MAPTMEN1KMT2ANPSR1CYP19A1 | |
| SCHEMBL10503149 | 0.73 | NFE2L2 (0.46) | MAPTMEN1KMT2ANPSR1NPC1 | |
| SCHEMBL10664614 | 0.70 | CYP24A1 (0.38) | MAPTMEN1KMT2ANPSR1NPC1 | |
| SCHEMBL10969706 | 0.70 | MEN1 (0.41) | MAPTMEN1KMT2ANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4017483-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1977-04-12 | — | — | US | disclosed |