Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 14/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 7/20 | 0.42 |
| ▸ | HTT | P42858 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11695579 | 0.80 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| SCHEMBL11698881 | 0.79 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| SCHEMBL11695352 | 0.78 | GFER (0.52) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| SCHEMBL11698149 | 0.72 | SLC16A3 (0.41) | ALDH1A1L3MBTL1MAPTKDM4EGAA | |
| SCHEMBL29397257 | 0.71 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| SCHEMBL56902 | 0.71 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| Charcoal, Activated SCHEMBL31112505 | 0.70 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| Ammonia Solution, Strong SCHEMBL28913421 | 0.70 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| SCHEMBL11697017 | 0.69 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1MAPTKDM4EHPGD | |
| SCHEMBL11696313 | 0.69 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4002616-A | POLYESTERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-01-11 | — | — | US | disclosed |
| US-3962220-A | ONE-STEP, AROMATIC ALDEHYDES, ACETIC ACID | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3962221-A | CONDENSATION, REDUCTION, OXIDATION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |