Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ESRRG | P62508 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11698881 | 0.84 | ALDH1A1 (0.51) | GFERSMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL26418339 | 0.83 | GFER (0.62) | GFERCYP2C19SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL22081629 | 0.83 | GFER (0.55) | GFERCYP2C19SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL11844854 | 0.83 | SNCA (0.40) | GFERCYP2C19SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL11695579 | 0.82 | ALDH1A1 (0.52) | SMN1; SMN2MAPTLMNAMEN1KMT2A | |
| SCHEMBL28568397 | 0.78 | KCNMA1 (0.66) | GFERCYP2C19SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL11698115 | 0.78 | ALDH1A1 (0.51) | GFERSMN1; SMN2MAPTLMNAMEN1 | |
| SCHEMBL12121363 | 0.77 | GFER (0.44) | GFERCYP2C19SMN1; SMN2CYP1A2MAPT | |
| SCHEMBL14428369 | 0.77 | MEN1 (0.50) | CYP2C19SMN1; SMN2CYP1A2MAPTMEN1 | |
| SCHEMBL14428398 | 0.76 | MEN1 (0.53) | CYP2C19SMN1; SMN2CYP1A2MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4002616-A | POLYESTERS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-01-11 | — | — | US | disclosed |
| US-3962220-A | ONE-STEP, AROMATIC ALDEHYDES, ACETIC ACID | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3962221-A | CONDENSATION, REDUCTION, OXIDATION | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |