Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583098 | 0.81 | KIF11 (0.38) | KIF11EGFRSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL2661233 | 0.80 | CHEK1 (0.55) | KIF11SMN1; SMN2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL13122112 | 0.76 | KIF11 (0.47) | KIF11EGFRSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL4796082 | 0.75 | FADS1 (0.61) | EGFRAXLTRPA1PLK3 | |
| SCHEMBL20674188 | 0.75 | KIF11 (0.46) | KIF11EGFRSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL4493290 | 0.75 | KIF11 (0.46) | KIF11EGFRSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL4240411 | 0.75 | KIF11 (0.46) | KIF11EGFRSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL2659927 | 0.74 | ALDH1A1 (0.54) | KIF11EGFRSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL1407075 | 0.72 | ALDH1A1 (0.49) | KIF11SMN1; SMN2KDM4EHSD17B10ALDH1A1 | |
| SCHEMBL13115644 | 0.72 | KIF11 (0.44) | KIF11EGFRSMN1; SMN2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4065568-A | 3-Carbo(lower alkoxy)hydrazinoindazoles | BAYER AKTIENGESELLSCHAFT (DT) | 1977-12-27 | — | — | US | disclosed |