Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.53 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.45 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6514251 | 0.91 | KMT2A (0.58) | LMNAPLA2G10PLA2G2ACALM1KMT2A | |
| Thiobenzoic Acid SCHEMBL29060734 | 0.80 | LMNA (0.55) | LMNAPLA2G10PLA2G2ACALM1KMT2A | |
| SCHEMBL7895911 | 0.80 | LMNA (0.55) | LMNAPLA2G10PLA2G2ACALM1KMT2A | |
| SCHEMBL20382745 | 0.78 | LMNA (0.64) | LMNAPLA2G10PLA2G2ACALM1KMT2A | |
| SCHEMBL21838338 | 0.78 | LMNA (0.53) | LMNAPLA2G10PLA2G2ACALM1KMT2A | |
| SCHEMBL10492823 | 0.78 | LMNA (0.64) | LMNAPLA2G10PLA2G2ACALM1KMT2A | |
| SCHEMBL7897904 | 0.78 | PLA2G10 (0.64) | LMNAPLA2G10PLA2G2ACALM1KMT2A | |
| SCHEMBL2772794 | 0.78 | LMNA (1.00) | LMNAPLA2G10PLA2G2ACALM1KMT2A | |
| SCHEMBL608234 | 0.78 | — | — | |
| SCHEMBL6581239 | 0.78 | LTA4H (0.57) | LMNAKMT2ALTA4HPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055652-A | 1-[β(R-thio)phenethyl]imidazoles and derivatives thereof | SYNTEX (U.S.A.) INC. (US) | 1977-10-25 | — | — | US | disclosed |