⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3656317 | 0.84 | SMN1; SMN2 (0.60) | — | |
| SCHEMBL5571005 | 0.78 | APP (0.52) | — | |
| SCHEMBL11698581 | 0.78 | LMNA (0.64) | — | |
| Thiobenzoic Acid SCHEMBL3229819 | 0.75 | CES1 (0.54) | — | |
| Thioacetamide SCHEMBL11747855 | 0.75 | ATM (0.50) | — | |
| Thiobenzoic Acid SCHEMBL7533370 | 0.75 | CES1 (0.54) | — | |
| SCHEMBL10877617 | 0.73 | CES2 (0.52) | — | |
| SCHEMBL10339337 | 0.73 | ALDH1A1 (0.50) | — | |
| SCHEMBL11844374 | 0.73 | ESR1 (0.56) | — | |
| SCHEMBL1035354 | 0.73 | ESR1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7807750-B2 | Thermally-reactive polymers | SURMODICS, INC. (US) | 2010-10-05 | — | — | US | claimed |
| EP-1807387-A2 | SUBSTITUTED TETRACYCLINE COMPOUNDS | Paratek Pharmaceuticals, Inc. (US) | 2007-07-18 | — | — | EP | claimed |
| CN-1819986-A | Preparation of 1, 3-diphenylprop-2-en-1-one derivatives | GENFIT (FR) | 2006-08-16 | — | — | CN | claimed |
| US-20060147847-A1 | Antimicrobial compositions and methods | Surmodics Coatings, LLC | 2006-07-06 | — | — | US | claimed |
| WO-2006047756-A2 | SUBSTITUTED TETRACYCLINE COMPOUNDS | PARATEK PHARMACEUTICALS, INC. (US) | 2006-05-04 | — | — | WO | claimed |
| WO-2006022920-A1 | THERMALLY-REACTIVE POLYMERS | SURMODICS, INC. (US) | 2006-03-02 | — | — | WO | claimed |
| US-20060030669-A1 | Thermally-reactive polymers | SURMODICS, INC. | 2006-02-09 | — | — | US | claimed |
| EP-0328668-A1 | NONLINEAR OPTICAL MATERIAL | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | claimed |
| EP-0264198-A2 | Optical information recording medium | CANON KABUSHIKI KAISHA (JP) | 1988-04-20 | — | — | EP | claimed |
| EP-4045605-B1 | CROSSLINKING COMPOSITIONS AND COATINGS FORMED THEREFROM | PPG IND OHIO INC (US) | 2023-12-06 | — | — | EP | disclosed |
| US-11827740-B2 | Crosslinking compositions and coatings formed therefrom | PPG INDUSTRIES OHIO, INC. (US) | 2023-11-28 | — | — | US | disclosed |
| US-11787771-B2 | Hydrazide containing nuclear transport modulators and uses thereof | Karyopharm Therapeutics Inc. (US) | 2023-10-17 | — | — | US | disclosed |
| US-20230293524-A1 | OTIC FORMULATIONS FOR DRUG-INDUCED OTOTOXICITY | SPIRAL THERAPEUTICS INC. | 2023-09-21 | — | — | US | disclosed |
| CN-113226271-B | Oral care compositions | 高露洁-棕榄公司 | 2023-07-25 | — | — | CN | disclosed |
| US-3948869-A | Process for polymerizing conjugated dienes | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1976-04-06 | — | — | US | disclosed |
| US-3943369-A | Liquid crystalline information transfer | XEROX CORPORATION (US) | 1976-03-09 | — | — | US | disclosed |
| US-3942871-A | Liquid crystalline optical filter | XEROX CORPORATION (US) | 1976-03-09 | — | — | US | disclosed |
| US-3942870-A | Liquid crystalline optical filter | XEROX CORPORATION (US) | 1976-03-09 | — | — | US | disclosed |
| US-3942872-A | Liquid crystalline display | XEROX CORPORATION (US) | 1976-03-09 | — | — | US | disclosed |
| US-3942007-A | Liquid crystalline image converter | XEROX CORPORATION (US) | 1976-03-02 | — | — | US | disclosed |