Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5255980 | 0.81 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2ATSHRGAA | |
| SCHEMBL30267851 | 0.80 | PTPRC (0.38) | HPGDALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL11811358 | 0.80 | PTPRC (0.38) | HPGDALDH1A1KDM4ETSHRTDP1 | |
| SCHEMBL17704659 | 0.76 | ESR1 (0.48) | HPGDALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11698902 | 0.76 | TSHR (0.42) | HPGDALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11699828 | 0.76 | SKP2 (0.52) | ALDH1A1MEN1KMT2AKDM4ETSHR | |
| SCHEMBL11699151 | 0.76 | ALOX15 (0.45) | — | |
| SCHEMBL8943857 | 0.76 | ALDH1A1 (0.46) | HPGDALDH1A1KMT2AKDM4EGAA | |
| SCHEMBL28122001 | 0.76 | MAPT (0.50) | HPGDALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL29783216 | 0.74 | HPGD (0.39) | HPGDALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042472-A | Electrolytic process for 7-methoxy-3-exomethylenecepham compounds | ELI LILLY AND COMPANY (US) | 1977-08-16 | — | — | US | disclosed |