Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | DBH | P09172 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL911100 | 0.83 | CA2 (0.61) | SMN1; SMN2HTTALDH1A1KDM4ELMNA | |
| SCHEMBL10947297 | 0.83 | MAPT (0.44) | MAPTSMN1; SMN2L3MBTL1HTTALDH1A1 | |
| SCHEMBL150589 | 0.82 | MAPT (0.50) | MAPTSMN1; SMN2L3MBTL1HTTALDH1A1 | |
| SCHEMBL9165578 | 0.80 | CRHBP (0.46) | MAPTSMN1; SMN2L3MBTL1HTTALDH1A1 | |
| SCHEMBL5068435 | 0.79 | MAPT (0.54) | MAPTSMN1; SMN2L3MBTL1HTTALDH1A1 | |
| SCHEMBL11579051 | 0.79 | KMT2A (0.51) | MAPTSMN1; SMN2ALDH1A1KDM4EGAA | |
| SCHEMBL910732 | 0.79 | CYP1A2 (0.62) | ALDH1A1GAAKMT2AMEN1LMNA | |
| SCHEMBL2500053 | 0.77 | MAPT (0.56) | MAPTSMN1; SMN2L3MBTL1HTTALDH1A1 | |
| SCHEMBL580639 | 0.77 | MAPT (0.56) | MAPTSMN1; SMN2L3MBTL1HTTALDH1A1 | |
| SCHEMBL29463290 | 0.77 | MAPT (0.56) | MAPTSMN1; SMN2L3MBTL1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432234-A | Method for preparing 1-phenylacetyl-beta-carboline derivatives | 中国药科大学 | 2017-02-22 | — | — | CN | disclosed |