Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA5 | P31644 | 4/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.52 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.52 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.52 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.52 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.52 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.52 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.52 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRE | P78334 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24524829 | 0.88 | GABRA5 (0.47) | GABRA5GABRB2GABRA1SLC6A1SLC6A12 | |
| SCHEMBL6264076 | 0.86 | GABRA5 (0.45) | GABRA5GABRB2GABRA1SLC6A1SLC6A12 | |
| SCHEMBL26077271 | 0.86 | GABRA5 (0.45) | GABRA5GABRB2GABRA1SLC6A1SLC6A12 | |
| SCHEMBL879294 | 0.86 | GABRA5 (0.45) | GABRA5GABRB2GABRA1SLC6A1SLC6A12 | |
| SCHEMBL14204666 | 0.83 | GNAI3 (0.43) | GABRA5GABRB2GABRA1SLC6A1SLC6A12 | |
| SCHEMBL44579 | 0.82 | GABRA5 (0.75) | GABRA5GABRB2GABRA1SLC6A1SLC6A12 | |
| SCHEMBL17653843 | 0.80 | EPHX1 (0.49) | GABRA5GABRB2GABRA1SLC6A1SLC6A12 | |
| SCHEMBL505815 | 0.80 | GABRA5 (0.48) | GABRA5GABRB2GABRA1SLC6A1SLC6A12 | |
| Hydrochloric Acid SCHEMBL1967312 | 0.80 | GABRA5 (0.72) | GABRA5GABRB2GABRA1SLC6A1SLC6A12 | |
| SCHEMBL4754506 | 0.80 | GABRA5 (0.48) | GABRA5GABRB2GABRA1SLC6A1SLC6A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064255-A | ANTIDEPRESSANTS | MAR-PHA SOCIETE D'ETUDES ET D'EXPLOITATION DE MARQUES (FR) | 1977-12-20 | — | — | US | disclosed |