Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11699116 | 1.00 | BACE1 (0.48) | BACE1SRD5A1SRD5A2HDAC1TRPA1 | |
| SCHEMBL6240189 | 0.93 | BACE1 (0.55) | BACE1SRD5A1SRD5A2HDAC1PTPN1 | |
| SCHEMBL7770389 | 0.90 | ALOX15 (0.49) | BACE1SRD5A1SRD5A2HDAC1KMT2A | |
| SCHEMBL7770394 | 0.90 | ALOX15 (0.49) | BACE1SRD5A1SRD5A2HDAC1KMT2A | |
| SCHEMBL7774963 | 0.84 | BACE1 (0.59) | BACE1SRD5A1SRD5A2KMT2ANPC1 | |
| SCHEMBL7774960 | 0.84 | BACE1 (0.59) | BACE1SRD5A1SRD5A2KMT2ANPC1 | |
| SCHEMBL27599815 | 0.83 | ALDH1A1 (0.56) | BACE1HDAC1TRPA1KMT2ANPC1 | |
| SCHEMBL7774912 | 0.83 | PTGER1 (0.65) | BACE1SRD5A1SRD5A2PTPN1KMT2A | |
| SCHEMBL7774914 | 0.83 | PTGER1 (0.65) | BACE1SRD5A1SRD5A2PTPN1KMT2A | |
| SCHEMBL7776786 | 0.82 | RXRA (0.51) | BACE1SRD5A1SRD5A2HDAC1PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115020670-A | MOFs modified silicon-based negative electrode material and preparation method thereof | 合肥国轩高科动力能源有限公司 | 2022-09-06 | — | — | CN | claimed |
| CN-113234235-B | Preparation method of meso-tetra (4-carboxyphenyl) zinc porphyrin-MOF material for detecting lead | 浙江理工大学 | 2022-04-01 | — | — | CN | claimed |
| CN-113234235-A | Preparation method of meso-tetra (4-carboxyphenyl) zinc porphyrin-MOF material for detecting lead | 浙江理工大学 | 2021-08-10 | — | — | CN | claimed |
| CN-114058007-B | Method for preparing polycarbonyl enol ester compound by catalyzing polymerization of alkyne carboxylic acid with organic base | 华南理工大学 | 2022-10-25 | — | — | CN | disclosed |
| CN-115020670-A | MOFs modified silicon-based negative electrode material and preparation method thereof | 合肥国轩高科动力能源有限公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-113234235-B | Preparation method of meso-tetra (4-carboxyphenyl) zinc porphyrin-MOF material for detecting lead | 浙江理工大学 | 2022-04-01 | — | — | CN | disclosed |
| CN-114058007-A | Method for preparing polycarbonyl enol ester compound by catalyzing polymerization of alkyne carboxylic acid with organic base | 华南理工大学 | 2022-02-18 | — | — | CN | disclosed |
| CN-113234235-A | Preparation method of meso-tetra (4-carboxyphenyl) zinc porphyrin-MOF material for detecting lead | 浙江理工大学 | 2021-08-10 | — | — | CN | disclosed |
| US-4017483-A | OPTICAL BRIGHTENERS | CIBA-GEIGY CORPORATION (US) | 1977-04-12 | — | — | US | disclosed |