Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 5/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | SHBG | P04278 | 2/20 | 0.39 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11699198 | 1.00 | NR3C1 (0.56) | NR3C1ARCYP19A1KMT2AHSD17B10 | |
| SCHEMBL11314335 | 0.92 | NR3C1 (0.56) | NR3C1ARCYP19A1KMT2AHSD17B10 | |
| SCHEMBL11702404 | 0.89 | NR3C1 (0.57) | NR3C1ARCYP19A1KMT2AHSD17B10 | |
| SCHEMBL11702398 | 0.89 | NR3C1 (0.57) | NR3C1ARCYP19A1KMT2AHSD17B10 | |
| SCHEMBL11699233 | 0.85 | NR3C1 (0.49) | NR3C1ARCYP19A1KMT2AHSD17B10 | |
| SCHEMBL11699239 | 0.85 | NR3C1 (0.49) | NR3C1ARCYP19A1KMT2AHSD17B10 | |
| SCHEMBL8470203 | 0.84 | NFKB1 (0.46) | NR3C1ARCYP19A1KMT2AHSD17B10 | |
| SCHEMBL8470202 | 0.84 | NFKB1 (0.46) | NR3C1ARCYP19A1KMT2AHSD17B10 | |
| SCHEMBL9070362 | 0.83 | NR3C1 (0.78) | NR3C1ARCYP19A1KMT2AHSD17B10 | |
| SCHEMBL9223554 | 0.83 | NR3C1 (0.78) | NR3C1ARCYP19A1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041055-A | SULFENYLATION, MICHAEL ADDITION, REACTION WITH THIOPHILE, HYDROLYSIS | THE UPJOHN COMPANY (US) | 1977-08-09 | — | — | US | claimed |