Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfamethizole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
| ▸ | LMNA | P02545 | 2/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | AKT1 | P31749 | 5/20 | 0.55 |
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA3 | P07451 | 2/20 | 0.54 |
| ▸ | CA6 | P23280 | 2/20 | 0.54 |
| ▸ | CA5A | P35218 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfamethizole SCHEMBL9292378 | 0.90 | ALDH1A1 (0.91) | ALDH1A1LMNAKMT2APKMHPGD | |
| Sulfamethizole SCHEMBL28693374 | 0.88 | ALDH1A1 (0.94) | ALDH1A1LMNAPKMHPGDAKT1 | |
| Sulfamethizole SCHEMBL26453 | 0.88 | ALDH1A1 (1.00) | ALDH1A1LMNAPKMHPGDAKT1 | |
| Sulfamethizole SCHEMBL1566142 | 0.87 | ALDH1A1 (0.97) | ALDH1A1LMNAPKMHPGDAKT1 | |
| Sulfamethizole SCHEMBL9018487 | 0.84 | ALDH1A1 (0.91) | ALDH1A1LMNAKMT2APKMHPGD | |
| Sulfamethizole SCHEMBL580299 | 0.84 | ALDH1A1 (0.91) | ALDH1A1LMNAPKMHPGDAKT1 | |
| Sulfamethizole SCHEMBL17261454 | 0.83 | ALDH1A1 (0.89) | ALDH1A1LMNAPKMHPGDAKT1 | |
| SCHEMBL1094305 | 0.83 | ALDH1A1 (0.72) | ALDH1A1LMNAMEN1KMT2APKM | |
| SCHEMBL5391648 | 0.82 | SMN1; SMN2 (0.64) | ALDH1A1LMNAMEN1KMT2APKM | |
| Sulfamethizole SCHEMBL2458190 | 0.81 | ALDH1A1 (0.71) | ALDH1A1LMNAMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112679734-B | Soluble polyimide containing bis (trifluoromethyl) benzene substituted asymmetric meta-position structure and preparation method thereof | 常州大学 | 2022-06-17 | — | — | CN | claimed |
| CN-113708007-A | Polyimide/polyetherimide composite film and preparation method thereof | 北京宇程科技有限公司 | 2021-11-26 | — | — | CN | claimed |
| CN-112679734-A | Soluble polyimide containing bis (trifluoromethyl) benzene substituted asymmetric meta-position structure and preparation method thereof | 常州大学 | 2021-04-20 | — | — | CN | claimed |
| CN-110527293-A | A kind of Kapton and preparation method thereof of basalt scale fibre modification | INSTITUTE OF ADVANCED TECH OF HEILONGJIANG ACADEMY OF SCIENCES | 2019-12-03 | — | — | CN | claimed |
| CN-110511536-A | Composition epoxy resin and preparation method thereof | GUANGDONG ZHONGSEN IND DEVELOPMENT CO LTD | 2019-11-29 | — | — | CN | claimed |
| CN-107379724-B | A kind of high-color rendering quantum dot fluorescence powder film and preparation method thereof | 北京北达聚邦科技有限公司 | 2019-11-22 | — | — | CN | claimed |
| CN-110408003-A | A kind of preparation method of the biological base epoxy based on natural Cortex Magnoliae Officinalis derivative | UNIV DALIAN TECH | 2019-11-05 | — | — | CN | claimed |
| CN-110387194-A | A kind of manufacturing process of pressure-sensitive tape | 胡银松 | 2019-10-29 | — | — | CN | claimed |
| CN-110294920-A | A kind of high tenacity Weatherable resinous composition and its application | 陕西生益科技有限公司 | 2019-10-01 | — | — | CN | claimed |
| CN-110294995-A | A kind of vehicle spray painting LP blades primer base and preparation method | 江苏亚一智能装备有限公司 | 2019-10-01 | — | — | CN | claimed |
| CN-102604093-A | Preparation method of polyimide | CHANGCHUN HIPOLYKING CO LTD | 2012-07-25 | — | — | CN | claimed |
| CN-102443146-A | Starch and polylactic acid graft copolymer and synthesis method thereof | UNIV FUJIAN | 2012-05-09 | — | — | CN | claimed |
| CN-101591853-B | Fluorine-free nano durable super hydrophobicity finishing method for cellulose fabric | UNIV DONGHUA | 2011-08-31 | — | — | CN | claimed |
| CN-101591854-B | Nano durable super hydrophobicity finishing method for cellulose fabric | UNIV DONGHUA | 2011-07-20 | — | — | CN | claimed |
| CN-101591854-A | A kind of method for sorting of cellulosic fabric nano durable super hydrophobicity | UNIV DONGHUA (CN) | 2009-12-02 | — | — | CN | claimed |
| CN-101591853-A | A kind of method for sorting of cellulosic fabric fluorine-free nano durable super hydrophobicity | UNIV DONGHUA (CN) | 2009-12-02 | — | — | CN | claimed |
| CN-100489011-C | Proton-conducting membrane and use thereof | PEMEAS GMBH (DE) | 2009-05-20 | — | — | CN | claimed |
| CN-1732208-A | High molecular weight polyazoles | PEMEAS GMBH (DE) | 2006-02-08 | — | — | CN | claimed |
| CN-1606585-A | Proton conducting membrane and application thereof | CELANESE VENTURES GMBH (DE) | 2005-04-13 | — | — | CN | claimed |
| CN-1511170-A | Proton-conducting membrane and use thereof | �����ɷ� | 2004-07-07 | — | — | CN | claimed |