Sulfamethizole

Sulfamethizole

SCHEMBL26453

Cc1nnc(NS(=O)(=O)c2ccc(N)cc2)s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

folP

The experimentally established mechanism targets of Sulfamethizole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 1.00
LMNA P02545 2/20 1.00
PKM P14618 1/20 0.69
HPGD P15428 1/20 0.69
AKT1 P31749 6/20 0.68
CA1 P00915 3/20 0.67
CA2 P00918 3/20 0.67
CA12 O43570 1/20 0.67
CA3 P07451 1/20 0.67
CA6 P23280 1/20 0.67
CA5A P35218 1/20 0.67
CA9 Q16790 1/20 0.67
CA14 Q9ULX7 1/20 0.67
CA5B Q9Y2D0 1/20 0.67
CASP6 P55212 1/20 0.59
CTDSP1 Q9GZU7 1/20 0.59
TDP1 Q9NUW8 2/20 0.54
KDM4E B2RXH2 1/20 0.54
CYP2C9 P11712 1/20 0.54
EDNRA P25101 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfamethizole SCHEMBL1566142 0.98 ALDH1A1 (0.97) ALDH1A1LMNAPKMHPGDAKT1
Sulfamethizole SCHEMBL28693374 0.97 ALDH1A1 (0.94) ALDH1A1LMNAPKMHPGDAKT1
Sulfamethizole SCHEMBL9292378 0.96 ALDH1A1 (0.91) ALDH1A1LMNAPKMHPGDAKT1
Sulfamethizole SCHEMBL580299 0.96 ALDH1A1 (0.91) ALDH1A1LMNAPKMHPGDAKT1
Sulfamethizole SCHEMBL9018487 0.96 ALDH1A1 (0.91) ALDH1A1LMNAPKMHPGDAKT1
Sulfamethizole SCHEMBL17261454 0.94 ALDH1A1 (0.89) ALDH1A1LMNAPKMHPGDAKT1
Sulfamethizole SCHEMBL11699385 0.88 ALDH1A1 (0.78) ALDH1A1LMNAPKMHPGDAKT1
Sulfamethazine SCHEMBL28122262 0.88 ALDH1A1 (0.78) ALDH1A1LMNAPKMHPGDAKT1
SCHEMBL11893082 0.87 ALDH1A1 (0.77) ALDH1A1LMNAPKMHPGDAKT1
Sulfamethizole SCHEMBL3844013 0.86 ALDH1A1 (0.74) ALDH1A1LMNAPKMHPGDAKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 18237 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
US-20260091119-A1 ISOLATED TARGETED DELIVERY SYSTEM FOR THE TREATMENT OF GLIOMA CELLIS AG (CH) 2026-04-02 US claimed
US-12576124-B2 Formulation of a conjugate of a tubulysin analog to a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD (CN) 2026-03-17 US claimed
EP-4694929-A1 METHODS FOR TREATING CORNEAL INJURIES Lin, Sung-Jan (TW) 2026-02-18 EP claimed
US-20260027140-A1 COMPOSITIONS AND METHODS FOR TREATING AND AMELIORATING RESPIRATORY CONDITIONS AND INFLAMMATION OF MUCOSA ATOPIC MEDICAL INC (US) 2026-01-29 US claimed
US-20250388539-A1 3,3'-AROMATIC BIS(ETHER IMIDE)S, POLYETHERIMIDES THEREOF AND METHODS FOR MAKING SHPP GLOBAL TECH BV (NL) 2025-12-25 US claimed
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
US-12465623-B2 Use of parasites and extracellular vesicles obtained from parasites in cancer treatment YEDITEPE UNIVERSITESI (TR) 2025-11-11 US claimed
US-20250339551-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE DIFFERENT FUNCTIONAL SMALL MOLECULES FOR ENHANCED TREATMENT OF REFRACTORY DISEASES HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) 2025-11-06 US claimed
EP-0197521-A2 Immunoglobulin adsorbent and adsorption apparatus TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) 1986-10-15 EP claimed
EP-0171054-A2 Body fluid purification medium and apparatus TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION (JP) 1986-02-12 EP claimed
US-4186184-A Selective administration of drug with ocular therapeutic system ALZA CORPORATION (US) 1980-01-29 US claimed
US-4169763-A OF A CORYNEBACTERIA RESISTANT TO ASPARTIC ACID ANALOGS AND SULFA DRUGS KYOWA HAKKO KOGYO CO., LTD. (JP) 1979-10-02 US claimed
US-4122158-A FOR TREATMENT OF BURNS; BIODEGRADABLE HYDROPHOBIC POLYMER; SUSTAINED RELEASE ALZA CORPORATION (US) 1978-10-24 US claimed
US-4016251-A Vaginal drug dispensing device ALZA CORPORATION (US) 1977-04-05 US claimed
US-4014335-A Ocular drug delivery device ALZA CORPORATION (US) 1977-03-29 US claimed
US-3983209-A HYDROPHOBIC BIOERODIBLE POLYMER, MICROBIOCIDE OR PROTEOLYTIC ENZYME ALZA CORPORATION (US) 1976-09-28 US claimed
US-3968201-A POLYMER PHARMACIA AKTIEBOLAG (SW) 1976-07-06 US claimed
US-3933745-A Imide copolymers possessing hydroxyl groups RHONE-POULENC S.A. (FR) 1976-01-20 US claimed