Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18713938 | 0.83 | SKP2 (0.53) | ALDH1A1TDP1CYP3A4GAALMNA | |
| SCHEMBL11242750 | 0.83 | TP53 (0.46) | ALDH1A1TDP1CYP3A4GAALMNA | |
| SCHEMBL8750643 | 0.80 | NPC1 (0.42) | ALDH1A1TDP1GAALMNATP53 | |
| SCHEMBL14661925 | 0.80 | ALDH1A1 (0.43) | ALDH1A1TDP1CASP1CYP3A4GAA | |
| SCHEMBL15732192 | 0.80 | ALDH1A1 (0.41) | ALDH1A1TDP1CASP1CYP3A4GAA | |
| SCHEMBL19240330 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TDP1CASP1CYP3A4GAA | |
| SCHEMBL19175110 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TDP1CASP1CYP3A4GAA | |
| SCHEMBL6867025 | 0.78 | ALDH1A1 (0.54) | ALDH1A1TDP1CASP1CYP3A4GAA | |
| SCHEMBL9217580 | 0.78 | GAA (0.41) | ALDH1A1GAALMNATP53CA2 | |
| SCHEMBL1006507 | 0.78 | IDO1 (0.47) | ALDH1A1CYP3A4GAALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2736904-B1 | OXAZOLE AND THIAZOLE DERIVATIVES AS SELECTIVE PROTEIN KINASE INHIBITORS (C-KIT) | AB SCIENCE (FR) | 2016-03-16 | — | — | EP | disclosed |
| EP-2736904-B1 | OXAZOLE AND THIAZOLE DERIVATIVES AS SELECTIVE PROTEIN KINASE INHIBITORS (C-KIT) | AB SCIENCE (FR) | 2016-03-16 | — | — | EP | disclosed |
| US-9168245-B2 | Selective protein kinase inhibitors | AB SCIENCE (FR) | 2015-10-27 | — | — | US | disclosed |
| US-9168245-B2 | Selective protein kinase inhibitors | AB SCIENCE (FR) | 2015-10-27 | — | — | US | disclosed |
| US-9168245-B2 | Selective protein kinase inhibitors | AB SCIENCE (FR) | 2015-10-27 | — | — | US | disclosed |
| US-20140179698-A1 | SELECTIVE PROTEIN KINASE INHIBITORS | AB SCIENCE (FR) | 2014-06-26 | — | — | US | disclosed |
| EP-2736904-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AS SELECTIVE PROTEIN KINASE INHIBITORS (C-KIT) | AB Science (FR) | 2014-06-04 | — | — | EP | disclosed |
| WO-2013014170-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AS SELECTIVE PROTEIN KINASE INHIBITORS (C-KIT) | AB SCIENCE (FR) | 2013-01-31 | — | — | WO | disclosed |
| WO-2013014170-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AS SELECTIVE PROTEIN KINASE INHIBITORS (C-KIT) | AB SCIENCE (FR) | 2013-01-31 | — | — | WO | disclosed |
| US-8304547-B2 | Azolecarboxamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2012-11-06 | — | — | US | disclosed |
| US-4046554-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1977-09-06 | — | — | US | disclosed |
| US-3966811-A | HERBICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1976-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140179698-A1 | SELECTIVE PROTEIN KINASE INHIBITORS | KIT, MAP3K1, PRKCH | ALDH1A1 2869/4885TDP1 1761/4885CASP1 2454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.