Sugi Predict

Sugi Predict / Compounds / SCHEMBL6867025

SCHEMBL6867025

SCHEMBL6867025

Cc1ccc(Cc2ccc(C)c(N)c2)cc1N

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 9/20 0.54
▸ TDP1 Q9NUW8 3/20 0.54
▸ CASP1 P29466 1/20 0.54
▸ GAA P10253 3/20 0.54
▸ CYP3A4 P08684 5/20 0.50
▸ PARP1 P09874 1/20 0.49
▸ MAPT P10636 3/20 0.48
▸ KDM4E B2RXH2 3/20 0.48
▸ ESR1 P03372 1/20 0.48
▸ ESR2 Q92731 1/20 0.48
▸ MEN1 O00255 1/20 0.48
▸ POLB P06746 1/20 0.48
▸ RAB9A P51151 1/20 0.48
▸ KMT2A Q03164 1/20 0.48
▸ ALOX15 P16050 2/20 0.44
▸ HSD17B10 Q99714 2/20 0.44
▸ CYP1A2 P05177 1/20 0.44
▸ CASP7 P55210 1/20 0.44
▸ HIF1A Q16665 1/20 0.44
▸ TSHR P16473 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13964420 0.93 ALDH1A1 (0.48) ALDH1A1TDP1CASP1GAACYP3A4
SCHEMBL2119535 0.91 ALDH1A1 (0.58) ALDH1A1TDP1CASP1GAACYP3A4
SCHEMBL9610058 0.91 SKP2 (0.53) ALDH1A1TDP1CASP1GAACYP3A4
SCHEMBL24684583 0.88 GAA (0.44) ALDH1A1TDP1CASP1GAACYP3A4
SCHEMBL22939706 0.88 CYP3A4 (0.53) ALDH1A1TDP1CASP1GAACYP3A4
SCHEMBL12172512 0.86 CASP1 (0.52) ALDH1A1TDP1CASP1GAACYP3A4
SCHEMBL8211010 0.83 ALDH1A1 (0.52) ALDH1A1TDP1CASP1GAACYP3A4
SCHEMBL5005675 0.83 TDP1 (0.52) ALDH1A1TDP1CASP1CYP3A4PARP1
SCHEMBL10510941 0.82 TDP1 (0.48) ALDH1A1TDP1CASP1GAACYP3A4
SCHEMBL13004658 0.82 ALDH1A1 (0.59) ALDH1A1TDP1GAACYP3A4PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021022224-A1 COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF THEIR USE IN THE INHIBITION OF INTERACTION BETWEEN IL18 AND IL18R BETH ISRAEL DEACONESS MEDICAL CENTER, INC. (US) 2021-02-04 — — WO disclosed
CN-110461814-A Resin blend, prepreg and product containing phthalonitrile reactive diluent and bi-phthalonitrile resin 3M INNOVATIVE PROPERTIES CO 2019-11-15 — — CN disclosed
US-10208031-B2 Photocrosslinkable materials comprising alicyclic group ROLIC AG (CH) 2019-02-19 — — US disclosed
CN-108884023-A Bisphenol M bisphthalonitrile ether resin, bisphenol P bisphthalonitrile ether resin, preparation methods thereof, resin blend and two-component system 3M创新有限公司 2018-11-23 — — CN disclosed
CN-107586048-A Delamination glass container with refractory coating 康宁股份有限公司 2018-01-16 — — CN disclosed
CN-104520248-B Delamination resistant glass container with heat resistant coating 康宁股份有限公司 2017-10-31 — — CN disclosed
CN-105283312-B Substrate for organic electronic device 乐金显示有限公司 2017-05-17 — — CN disclosed
CN-103890859-B Insulating material for electronic devices 株式会社LG化学 2017-02-22 — — CN disclosed
CN-105283312-A Substrate for organic electronic device LG CHEMICAL LTD 2016-01-27 — — CN disclosed
CN-103890859-A Insulating material for electronic devices LG CHEMICAL LTD 2014-06-25 — — CN disclosed
US-4348318-A DYEING AND PRINTING TEXTILES; MONOAZO, TRIAZINE, HYDRAZONE, AND PYRAZOLONE DYES CIBA-GEIGY CORPORATION (US) 1982-09-07 — — US disclosed
US-4340536-A Chrome-complex dyes and the production and use thereof CIBA-GEIGY CORPORATION (US) 1982-07-20 — — US disclosed
EP-0009466-B1 1 : 2-BIS-CHROMIUM-COMPLEX DYESTUFFS FROM POLYAZO- OR DISAZO-AZOMETHINE COMPOUNDS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1982-05-19 — — EP disclosed
US-4311641-A Chromium complexes of mixed azo compounds CIBA-GEIGY CORPORATION (US) 1982-01-19 — — US disclosed
EP-0005207-B1 BIS-1:2 CHROME-DISAZO-BISAZO METHINE DYESTUFFS, THEIR PREPARATION AND USE FOR DYEING OF LEATHER CIBA-GEIGY AG (CH) 1981-12-09 — — EP disclosed
US-4256633-A AZO DYES; AZOMETHINE DYES; WOOL, POLYAMIDES, AND LEATHER CIBA-GEIGY CORPORATION (US) 1981-03-17 — — US disclosed
EP-0019851-A1 1:2 Chromium complex dyestuffs of the azomethine and/or azo series, their preparation and use in dyeing and printing polyamide or cellulose materials CIBA-GEIGY AG (CH) 1980-12-10 — — EP disclosed
EP-0012716-A1 Monochlorotriazine dyestuffs of the pyrazolone series, their preparation and their use for dyeing and printing textile materials CIBA-GEIGY AG (CH) 1980-06-25 — — EP disclosed
EP-0009466-A1 1 : 2-Bis-chromium-complex dyestuffs from polyazo- or disazo-azomethine compounds, their preparation and their use CIBA-GEIGY AG (CH) 1980-04-02 — — EP disclosed
EP-0005207-A2 Bis-1:2 chrome-disazo-bisazo methine dyestuffs, their preparation and use for dyeing of leather CIBA-GEIGY AG (CH) 1979-11-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10208031-B2 Photocrosslinkable materials comprising alicyclic group DDC, ALAD, DYNC1LI1 ALDH1A1 97/4885TDP1 840/4885CASP1 934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.