Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13638978 | 0.85 | SKP2 (0.55) | ALDH1A1TDP1CYP3A4SKP2MAPT | |
| SCHEMBL8750664 | 0.82 | NPC1 (0.36) | ALDH1A1CYP3A4SKP2MAPTNPC1 | |
| SCHEMBL11699485 | 0.80 | ALDH1A1 (0.46) | ALDH1A1TDP1CASP1CYP3A4SKP2 | |
| SCHEMBL5005675 | 0.77 | TDP1 (0.52) | ALDH1A1TDP1CASP1CYP3A4SKP2 | |
| SCHEMBL8251529 | 0.77 | DAO (0.43) | NPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL13696429 | 0.77 | ALDH1A1 (0.46) | ALDH1A1CYP3A4MAPTGAATSHR | |
| Ether SCHEMBL28280732 | 0.76 | CASP1 (0.71) | ALDH1A1TDP1CASP1CYP3A4MAPT | |
| SCHEMBL11970164 | 0.76 | GAA (0.57) | ALDH1A1CYP3A4MAPTGAATSHR | |
| SCHEMBL19240330 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TDP1CASP1CYP3A4SKP2 | |
| SCHEMBL19175110 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TDP1CASP1CYP3A4SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3253749-B1 | COMPOUNDS WITH ANTI-TUMORAL ACTIVITY | AB SCIENCE (FR) | 2021-12-08 | — | — | EP | disclosed |
| EP-3253749-B1 | COMPOUNDS WITH ANTI-TUMORAL ACTIVITY | AB SCIENCE (FR) | 2021-12-08 | — | — | EP | disclosed |
| EP-3053920-B1 | COMPOUNDS WITH ANTI-TUMORAL ACTIVITY | AB SCIENCE (FR) | 2020-04-08 | — | — | EP | disclosed |
| US-10570122-B2 | Compounds with anti-tumoral activity | AB SCIENCE (FR) | 2020-02-25 | — | — | US | disclosed |
| US-10570122-B2 | Compounds with anti-tumoral activity | AB SCIENCE (FR) | 2020-02-25 | — | — | US | disclosed |
| US-20180202388-A1 | PISTON FOR AN INTERNAL COMBUSTION ENGINE AND METHOD FOR PRODUCING THE PISTON FOR AN INTERNAL COMBUSTION ENGINE | FELT PRODUCTS MFG. CO. LLC | 2018-07-19 | — | — | US | disclosed |
| US-20180202388-A1 | PISTON FOR AN INTERNAL COMBUSTION ENGINE AND METHOD FOR PRODUCING THE PISTON FOR AN INTERNAL COMBUSTION ENGINE | FELT PRODUCTS MFG. CO. LLC | 2018-07-19 | — | — | US | disclosed |
| US-20180202388-A1 | PISTON FOR AN INTERNAL COMBUSTION ENGINE AND METHOD FOR PRODUCING THE PISTON FOR AN INTERNAL COMBUSTION ENGINE | FELT PRODUCTS MFG. CO. LLC | 2018-07-19 | — | — | US | disclosed |
| US-20180079747-A1 | COMPOUNDS WITH ANTI-TUMORAL ACTIVITY | AB SCIENCE (FR) | 2018-03-22 | — | — | US | disclosed |
| US-20180079747-A1 | COMPOUNDS WITH ANTI-TUMORAL ACTIVITY | AB SCIENCE (FR) | 2018-03-22 | — | — | US | disclosed |
| EP-3053920-A1 | Compounds with anti-tumoral activity | AB Science (FR) | 2016-08-10 | — | — | EP | disclosed |
| EP-2736904-B1 | OXAZOLE AND THIAZOLE DERIVATIVES AS SELECTIVE PROTEIN KINASE INHIBITORS (C-KIT) | AB SCIENCE (FR) | 2016-03-16 | — | — | EP | disclosed |
| EP-2736904-B1 | OXAZOLE AND THIAZOLE DERIVATIVES AS SELECTIVE PROTEIN KINASE INHIBITORS (C-KIT) | AB SCIENCE (FR) | 2016-03-16 | — | — | EP | disclosed |
| US-9168245-B2 | Selective protein kinase inhibitors | AB SCIENCE (FR) | 2015-10-27 | — | — | US | disclosed |
| US-9168245-B2 | Selective protein kinase inhibitors | AB SCIENCE (FR) | 2015-10-27 | — | — | US | disclosed |
| US-9168245-B2 | Selective protein kinase inhibitors | AB SCIENCE (FR) | 2015-10-27 | — | — | US | disclosed |
| US-20140179698-A1 | SELECTIVE PROTEIN KINASE INHIBITORS | AB SCIENCE (FR) | 2014-06-26 | — | — | US | disclosed |
| EP-2736904-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AS SELECTIVE PROTEIN KINASE INHIBITORS (C-KIT) | AB Science (FR) | 2014-06-04 | — | — | EP | disclosed |
| WO-2013014170-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AS SELECTIVE PROTEIN KINASE INHIBITORS (C-KIT) | AB SCIENCE (FR) | 2013-01-31 | — | — | WO | disclosed |
| WO-2013014170-A1 | OXAZOLE AND THIAZOLE DERIVATIVES AS SELECTIVE PROTEIN KINASE INHIBITORS (C-KIT) | AB SCIENCE (FR) | 2013-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570122-B2 | Compounds with anti-tumoral activity | MKI67, GZMB, RB1 | ALDH1A1 311/4885TDP1 2068/4885CASP1 334/4885 |
| US-20180079747-A1 | COMPOUNDS WITH ANTI-TUMORAL ACTIVITY | MKI67, TP53, VHL | ALDH1A1 318/4885TDP1 2264/4885CASP1 334/4885 |
| US-20140179698-A1 | SELECTIVE PROTEIN KINASE INHIBITORS | KIT, MAP3K1, PRKCH | ALDH1A1 2869/4885TDP1 1761/4885CASP1 2454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.