Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.64 |
| ▸ | IDO1 | P14902 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17069204 | 0.86 | IDO1 (0.56) | PNMTIDO1PYCR1 | |
| SCHEMBL9901109 | 0.78 | SLC7A5 (0.53) | IDO1HTR2ASLC6A3 | |
| SCHEMBL5241165 | 0.78 | IDO1 (0.48) | IDO1PYCR1 | |
| SCHEMBL17413477 | 0.78 | PNMT (1.00) | PNMTHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL3058411 | 0.78 | PNMT (1.00) | PNMTHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL3058413 | 0.78 | PNMT (1.00) | PNMTHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL30730196 | 0.78 | IDO1 (0.54) | IDO1PYCR1 | |
| SCHEMBL16649712 | 0.77 | PNMT (0.70) | PNMTHTR2AHTR2CHTR2BSLC6A2 | |
| SCHEMBL5240087 | 0.77 | IDO1 (0.47) | PNMTIDO1PYCR1 | |
| SCHEMBL11811734 | 0.77 | IDO1 (0.50) | IDO1PYCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4004032-A | ANOREXIGENIC AGENTS | BOEHRINGER INGELHEIM GMBH (DT) | 1977-01-18 | — | — | US | disclosed |
| US-3950335-A | APPETITE SUPPRESSANTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-13 | — | — | US | disclosed |
| US-3950335-A | APPETITE SUPPRESSANTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-13 | — | — | US | disclosed |